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Studies on the antidandruff activity of the essential oil of coleus amboinicus and eucalyptus globulus (Elsevier)

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  • Udaya school of Engiineering

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Objective: To determine the effect of the essential oil of Coleus amboinicus and Eucalyptus globules as potential antidandruff agent. Methods: Fresh leaves of Coleus amboinicus and Eucalyptus globules were collected from the Horticultural Research Station, Yercaud, Salem, Tamil Nadu, India. The collected leaves were washed thoroughly and shade dried for 7-10 days. The essential oils from both the dried plant leaves were obtained by hydro distillation procedure. The chemical compositions of hydro distilled essential oils were analyzed by Gas Chromatography-Mass spectrometry (GC-MS). The pure essential oils and the essential oils diluted with coconut oil of the two plants were used to check antidandruff activity against the dandruff causing fungus Malassezia furfur by agar well diffusion assay. Results: The average yield of essential oil from Coleus amboinicus (0.89%) and Eucalyptus globules (0.77%). The results of GC-MS revealed that the presence of eight compounds from Coleus amboinicus essential oil and five constituents from Eucalyptus globules representing 90.45% and 96.32% of the total oil respectively. The major component was identified as Thymol (phenolic rich compocnd) (41.3%) in Coleus amboinicus and in Eucalyptus globules the major constituents was 1-8, Cineol (91.61%). In the antidandruff activity the broad range of inhibitory zone was observed in Eucalyptus globules (37mm) oil compare to Coleus amboinicus (31mm). Ketaconazole based shampoo used as a standard. Conclusion: This study would direct to the establishment of a natural compound from Coleus amboinicus and Eucalyptus globules as an antidandruff agent which can be used for the production of potential antifungal drug and novel pharmaceutical and cosmeceutical leads.
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... On the other hand, the major constituents of E. camaldulensis growing in Kenya have been reported as α-pinene (15.6%), 1,8-cineole (16.2%), and α-phellandrene (10%) 34 . Similarly, variations in the volatile constituents of E. globulus growing in different areas of the world have been reported 30,33,[35][36][37][38][39][40] . For example, the percentage of 1,8-cineole in E. globulus growing in China and Algeria has been reported as 72.71% and 55.29%, respectively 33,35,40 . ...
... The volatile oil yields were determined based on the weight of the fresh leaf material, resulting in yields of 2.5% and 3.13% (v/w), respectively. The yield percentages obtained from both plants growing in the central region of Saudi Arabia were higher than those reported for plants grown in other parts of the world 30,32,[34][35][36][37][38][39]51 . Specifically, the volatile oil yield percentage from E. camaldulensis (2.5%) obtained in this study was found to be higher than yields reported for the same plant grown in Italy (0.2-0.5%), Benin (0.6-1.4%), Kenya (0.5%), Pakistan (1-2.25%), and Ethiopia (1.2%) 31,32,34,40,52 . ...
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Eucalyptus is a fragrant plant with a highly volatile oil content grown worldwide. This study investigated the phytochemical and biological features of two Eucalyptus species, E. camaldulensis and E. globulus, cultivated in Central Saudi Arabia. Phytochemical analysis revealed 17 compounds in E. camaldulensis and 13 in E. globulus, with α-pinene and 1,8-cineole being both plants' most abundant volatile components. The antimicrobial activity revealed that Salmonella typhimurium ATCC 13311 and Candida albicans ATCC 10231 are the most susceptible to E. camaldulensis, with the zone of inhibition diameters (ZIDs) of 17.0 ± 0.2 mm and 22.0 ± 0.3 mm, respectively. In contrast, for E. globulus, methicillin-resistant Staphylococcus aureus and Candida albicans ATCC 10231 were the most susceptible, with ZIDs of 13.0 ± 0.2 mm and 20.0 ± 0.2 mm, respectively. E. camaldulensis had minimum inhibitory concentration (MIC) range from 1.56 to 12.5 µL/mL, minimum biocidal concentration (MBC) range from 3.125 to 25.0 µL/mL, minimum biofilm inhibitory concentration (MBIC) range from 3.125 to 25.0 µL/mL, and minimum biofilm eradication concentration (MBEC) from 6.25 to 50.0 µL/mL, while E. globulus had MIC range from 3.125 to 12.5 µL/mL, MBC range from 6.25 to 25.0 µL/mL, MBIC range from 6.25 to 25.0 µL/mL, and MBEC range from 12.5 to 50.0 µL/mL, for the tested organisms. E. camaldulensis demonstrated better antimicrobial activity than E. globulus against the tested organisms, making it a promising antimicrobial drug candidate. Further research is required to determine its effectiveness in treating different human infections.
... Herbs such as Moringa leaves (Moringa oleifera), Mexican mint leaves (Coleus amboinicus) and Hibiscus leaves (Hibiscus rosa-sinensis) were chosen carefully for testing their antifungal properties against dandruff-causing species [7][8][9][10] . ...
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Today, the world is developing more and more in all sectors at a faster pace. But with all these developments, people are more prone to falling ill due to factors such as pollution, unhealthy lifestyles, busy work schedules, etc. Nowadays, even children suffer from the issue of dandruff and scalp infections which in later teenage years leads to unhealthy scalp and hair fall problems. Dandruff is a common scalp condition that affects individuals of all ages. It not only causes discomfort but also undermines hair health and aesthetics. Although scalp disorders are not among those that cause severe physical illness or morbidity yet are of great social concern. Scalp and hair conditions have more of a psychological impact on societies. Even minor changes in hair like graying of hair, affects the self-confidence and self-esteem of an individual. There are many types of medications and formulations to treat hair dandruff issues, one of which includes a novel drug delivery system such as “Emulgel” in the form of a mask. The anti-dandruff hair mask offers multiple benefits, including reduction in scalp inflammation and effective management of hair dandruff problems. Furthermore, it rejuvenates the scalp and nourishes hair follicles due to its natural vitamins and nutrient content. Keywords: Dandruff, Pityriasis capitis, Seborrheic dermatitis, Mexican mint, Herbal hair mask, Hair mask
... It is composed mostly of water (89.78% ± 0.10), with solid contents near to 10.22%. In the majority, it is composed of ashes (7.13% ± 0.03) and phytochemical compounds, like α-pinene, β-pinene, thymol, carvacrol, 1,8-cineole, p-cymene and, β-caryophyllene, as suggest Selvakumar et al. (2012) and Roshan et al. (2010). Characteristics such as low acidity and neutral pH (7.89 ± 0.02) favor the inclusion of this component in food matrices without DE MENDONÇA ET AL. impairing the sensorial characteristics and, in the case of bread, without modifying the optimum pH of fermentative activity. ...
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Background and Objectives The potential of Plectranthus amboinicus aqueous extract (PAAE) to enhance the quality properties of wheat bread was investigated. PAAE was incorporated as an ingredient in bread formulations to improve shelf life. Findings The results indicate that the technological characteristics of bread formulations were enhanced with the inclusion of up to 75% PAAE. This enhancement led to increased specific volume and expansion properties. Scanning electron microscopy analysis demonstrated improved interaction between gluten and starch. PAAE exhibited potential in retarding bread hardening and preventing mold growth. Conclusions PAAE holds promise as a novel ingredient for use in baked products. Its inclusion in bread formulations significantly improved technological characteristics, including specific volume and color, and positively influenced the interaction between gluten and starch. Additionally, PAAE showed potential in extending the shelf life of bread and inhibiting fungal growth. Significance and Novelty This study is significant due to the introduction of a novel ingredient, PAAE, in the field of baking. The incorporation of this extract represents an innovation in the quest for improvements in the nutritional and technological properties of baked goods. The ability of PAAE to function as an antifungal agent holds great relevance for the food industry.
... P. amboinicus and O. sanctum comprise some main phytochemical constituents such as α-Cubebene, α-Copaene, alpha-Humulene, Beta-caryophyllene, Carvacrol, Eugenol, Para-cymene, Limonene, Apigenin, Rosmarinic acid, Ursolic acid, Oleanolic acid, Luteolin, Beta-sitosterol, etc., 17,[21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40] . As per the literature study, these are typically the components of major interest with bioactive properties that are well established. ...
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