hERG channel function: Beyond long QT

Article (PDF Available)inActa Pharmacologica Sinica 34(3):329-35 · March 2013with31 Reads
DOI: 10.1038/aps.2013.6 · Source: PubMed
To date, research on the human ether-a-go-go related gene (hERG) has focused on this potassium channel's role in cardiac repolarization and Long QT Syndrome (LQTS). However, growing evidence implicates hERG in a diversity of physiologic and pathological processes. Here we discuss these other functions of hERG, particularly their impact on diseases beyond cardiac arrhythmia.

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Available from: PubMed Central, Jan 16, 2014 · License: CC BY-NC-ND
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