Dimensional Control of Cancer Cell Migration

Department of Chemical and Biomolecular Engineering, and Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University, Baltimore, Maryland. Electronic address: .
Biophysical Journal (Impact Factor: 3.97). 01/2013; 104(2):279-80. DOI: 10.1016/j.bpj.2012.12.016
Source: PubMed

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    • "The cross-sectional areas (Wolf et al., 2009) of pores/channels encountered in vivo range from 10 to >300 mm 2 , suggesting that cells migrating in vivo experience varying degrees of physical confinement. Mounting evidence suggests that physical confinement alters cell migration mechanisms (Balzer et al., 2012; Konstantopoulos et al., 2013; Pathak and Kumar, 2012; Stroka et al., 2013). "
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