Characteristics of B-cell lymphomas in HIV/HCV-coinfected patients during the combined antiretroviral therapy era: an ANRS CO16 LYMPHOVIR cohort study
Hepatitis C virus (HCV) infection is frequent among HIV infected patients. We describe the characteristics of 6 HIV-HCV coinfected patients with B-cell non-Hodgkin lymphoma (NHL) included in a prospective cohort study of HIV related lymphomas. Five of the six cases had features of marginal zone/lymphoplasmacytic NHL versus one out of 33 HIV only infected patients. Remarkably, anti-HCV treatment led to a hematological response in a patient with splenic marginal zone lymphoma. This supports the role of chronic antigenic stimulation by HCV on lymphomagenesis and further evaluation of HCV antiviral therapy in coinfected patients with NHL.
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.