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Research and Development in Ayurveda -An overview

Authors:
  • Central Council for Research in Ayurvedic Sciences

Abstract

Quest for healthy and long life is perhaps as old as human existence and efforts are unremitting to address the challenges and triumph over the bottlenecks across this journey. Ayurveda –the science of life, evolved as a comprehensive system of healthcare systematically through scientific experimentations of high order backed by sound and reproducible evidence base and stood the test of the time. Natural products of botanical, Animal or mineral sources from India have initiated the scientific expedition of Drugs since antiquity .Even now more than fifty percent of existing drugs can be traced to natural products used globally. Still, more interesting leads are emerging for drug discovery from Ayurvedic drugs. Several strategies and roadmaps are being drawn to carry forward merits of this science so as to meet the current day heath needs and mainstream its core strengths alongside through research & development (R&D) in this country and across the globe. Some of the Ayurvedic plants, which have led to global use and pharmacology research viz. Aloe vera in Burns management ; Curcuma longa as Anti-inflammatory, Anti- diabetic & Cancer preventive agent etc. The evidence base of Ayurveda established since ancient times calls for further substantiation and such research will require integration of Ayurveda and bio medicine . Research methodology entails the approach of ‘system validation’ and protocols evolved through a strong frontier with modern science, all together without losing core foundations of its basic tenets and fundamental thoughts.
... The holistic approach is the 'strength' of Ayurveda. This approach poses considerable difficulty owing to diverse concepts and complex approaches in clinical trial design, diagnosis & therapy, assessment of outcomes of clinical efficacy and drug interactions pose certain limitations in research such as.[28]1 ...
Article
Full-text available
Diabetes mellitus (madhumeha) is one amongst the refractory disease conditions recognized by medical scholars of ancient India. Ayurvedic literatures vividly describe about the etiology, pathogenesis, prognosis, complications, its management and scientifically attributed the causal relationship of dietary, lifestyle, environmental and genetic factors. The treatment modalities are designed and recommended based on type and stage of disease. Furthermore many classical references to use dosage forms of single plant drugs and compound formulations, which are vogue in clinical practice call for further scientific validation for their attributes, principles and extent of use. Despite of recent progression in medical science, several challenges still exist in the management of diabetes that requires special attention to develop unexplored fields of medical knowledge. Ayurveda offers comprehensive safe and effective approaches to manage such conditions. Designing pertinent research model is a key challenge behind the examination of Safety and efficacy of Ayurvedic interventions satisfying its fundamental principles and systems approach. Despite of challenges and constrains, some experimental and clinical studies on Ayurvedic approaches and therapies provide scientific evidence on efficacy and safety.
... Challenges and Scope: The holistic approach is the 'strength' of Ayurveda. This approach poses considerable difficulty owing to diverse concepts and complex approaches in clinical trial design, diagnosis & therapy, assessment of outcomes of clinical efficacy and drug interactions pose certain limitations in research such as ( Srikanth, et al., 2013). • Standardization and Quality Control • Complexity of dosage forms/delivery System • Diverse concepts • Complex approaches in • Clinical Trial Design • Diagnosis & Therapy • Clinical Efficacy /Outcome measures • Drug Interactions / interventions of different systems • Mechanism of action (MoA) studies • Synchronization of Ayurveda and bio-medicine approaches An appropriate model addressing the above issues would certainly facilitate in designing research plans satisfying fundamental principles of Ayurveda. ...
Conference Paper
Full-text available
Diabetes mellitus (madhumeha) is one amongst the refractory disease conditions recognized by medical scholars of ancient India. Ayurvedic literatures vividly describe about the etiology, pathogenesis, prognosis, complications, its management and scientifically attributed the causal relationship of dietary, lifestyle, environmental and genetic factors .The treatment modalities are designed and recommended based on type and stage of disease. Furthermore many classical references to the use dosage forms of single plant drugs and compound formulations, which are vogue in clinical practice call for further scientific validation for their attributes, principles and extent of use. Despite of recent progression in medical science, several challenges still exist in the management of diabetes that require special attention to develop un- explored fields of medical knowledge. Ayurveda offers comprehensive safe and effective approaches to mange such conditions. Designing pertinent research model is a key challenge behind the examination of safety efficacy of Ayurvedic interventions satisfying its fundamental principles and systems approach. Despite of challenges and constrains, some experimental and clinical studies on Ayurvedic approaches and therapies provide scientific evidence on efficacy and safety
Article
Full-text available
From historical point of view it is evident that Ayurvedic drugs and procedure based therapies are exceedingly used in alleviating wide range of ocular conditions. Shalakya-tantra-the core engrossing specialty of Ayurveda, deals with management of ocular illness and has been significantly contributing to the eye care. In this study is an attempt has been made to present the data on healthcare seeking behavior and utilization pattern among the patients attending Ayurvedic ophthalmic and treatment facility located at Ayurveda Central Research Institute of (a CCRAS Research Institute), New Delhi, for various eye maladies. The data generated during the period 2010 -2015 repossessed from the records, annual reports and analyzed by using appropriate scientific methods and presented. The study revealed preference of the patients towards Ayurveda for chronic and refractory ocular illness such as retinitis pigmentosa, age related macular degeneration, diabetic retinopathy including other diseases of retina, glaucoma, optic neuropathy etc. Further the pattern of follow-ups and year wise attendance pattern of patents are indicative of growing interest towards Ayurveda based eye care.Such information would certainly provide an insight on perception of users of Ayurveda approaching for ophthalmic services.
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