The concept of evidence-based practice is helping early educators, special educators, early interventionists, child care professionals, mental health professionals, social workers, health care professionals, and others to transform the services provided to children and families. The authors discuss the emergence of the evidence-based practice movement and the challenges of integrating what we know from scientific research into daily practice with children and families. The authors define evidence-based practice for the early childhood field as "a decision-making process that integrates the best available research evidence with family and professional wisdom and values" and suggest that evidence-based practice is essentially a process or way of empowering professionals and others to integrate various sources of knowledge to make informed decisions that directly benefit children and families.