HLA-A*3318, a novel allele, identified by sequence-based typing in a Chinese individual

Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong Province, China.
Tissue Antigens (Impact Factor: 2.14). 10/2008; 72(6):600-2. DOI: 10.1111/j.1399-0039.2008.01150.x
Source: PubMed


We report a novel human leucocyte antigen (HLA)-A allele, officially named as A*3318, which was found during high-resolution sequence-based typing in a Chinese potential hematopoietic stem cell transplantation donor. Compared with the HLA-A*330301 sequence, the A*3318 has one nucleotide substitution in exon 3: at nt 413 where A-->G resulting in an amino acid substitution from Q (CAG) to R (CGG) at codon 114.

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