Nursing Guidelines for Administration of Immunoglobulin Replacement Therapy.

and Duke University, Durham, North Carolina (Ms Sedlak). Mary Elizabeth M. Younger, PhD, CRNP, is a pediatric nurse practitioner in the Division of Pediatric Immunology at Johns Hopkins in Baltimore, Maryland. She has extensive experience with managing immunoglobulin therapy for hundreds of antibody-deficient patients. Loris Aro, RN, is employed as a patient nurse educator and clinical research coordinator at Sussman and Associates Immunology in Toronto, Ontario, Canada. William Blouin, MSN, ARNP, CPNP, works in allergy/immunology at Miami Children's Hospital. With more than 35 years of experience in pediatrics, his interests and expertise are in the areas of allergy, HIV, immunology, infusion, and transplantation. Carla Duff, MSN, CPNP, CCRP, is a pediatric nurse practitioner in the Division of Pediatric Allergy and Immunology at the University of South Florida/All Children's Hospital in St. Petersburg, Florida. She has many years of experience with clinical immunology and managing immunoglobulin replacement therapy for primary immunodeficient patients. Kristin B. Epland, MSN, FNP, is a family nurse practitioner specializing in the care and diagnosis of primary immunodeficiencies and autoimmune diseases. She has worked with immune-deficient children and adults through home infusion nursing and now at the Midwest Immunology Clinic and Infusion Center in Plymouth, Minnesota. Elyse Murphy, BSN, RN, is a medical science liaison with CSL Behring with expertise in immunoglobulin therapies and more than 30 years of experience in the disease state areas of immunology, hematology-oncology, neurology, and transplant. Debra Sedlak, CPNP, has more than 25 years of experience in clinical immunology with the division of Pediatric Allergy and Immunology at Duke University Medical Center, Durham, North Carolina. The Immune Deficiency Foundation (IDF) was founded in 1980 to improve the diagnosis, treatment, and quality of life of persons with primary immunodeficiency through advocacy, education, and research. The IDF Nurse Advisory Committee is composed of 11 nurses who together have hundreds of years of nursing experience in meeting the needs of this patient population and facilitating the mission of the IDF (
Journal of infusion nursing: the official publication of the Infusion Nurses Society 01/2013; 36(1):58-68. DOI: 10.1097/NAN.0b013e3182798af8
Source: PubMed


Immunoglobulin (Ig) replacement therapy, given as regular infusions of pooled human Ig, is the recognized treatment of humoral immunodeficiencies characterized by hypogammaglobulinemia and impaired antibody responses. It is a safe, effective therapy when delivered by nurses who have been educated to oversee and/or provide these infusions. Guidelines for administration have been developed by the Immune Deficiency Foundation Nurse Advisory Committee to provide a framework and guidance to those nurses administering this therapy.

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