Contrast alternatives for iodinated contrast allergy and renal dysfunction: Options and limitations

Division of Interventional Radiology, Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa.
Journal of vascular surgery: official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter (Impact Factor: 3.02). 12/2012; 57(2). DOI: 10.1016/j.jvs.2012.10.009
Source: PubMed


Diagnostic angiography and vascular interventions make routine use of iodinated contrast material (ICM). Patients with renal disease or contrast allergy pose limitations on the use of ICM. In such cases, alternative contrast media may be used to carry out the procedure. Current alternatives include carbon dioxide, gadolinium, and dilute ICM. Each of these alternatives has its own unique features and limitations. In the present review article, the current alternatives to ICM are explored, with a focus on the applications and restrictions of each.

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    • "It is particularly useful in patients who are hypersensitive to iodinated contrast or have compromised renal function [9]. We report the first case of CO 2 gas embolism causing multiple diffuse bilateral strokes in a patient undergoing CO 2 angiogram for thrombosed AV fistula. "

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