Polyphenolic Profile and Biological Activity of Chinese Hawthorn (Crataegus pinnatifida BUNGE) Fruits

Department of Natural and Informatics Sciences, Faculty of Central European Studies, Constantine the Philosopher University in Nitra, Drazovska 4, SK-949 74 Nitra, Slovak Republic. .
Molecules (Impact Factor: 2.42). 12/2012; 17(12):14490-14509. DOI: 10.3390/molecules171214490
Source: PubMed


Chinese hawthorn (Crataegus pinnatifida Bge.) fruits are rich in polyphenols (e.g., epicatechin, procyanidin B2, procyanidin B5, procyanidin C1, hyperoside, isoquercitrin and chlorogenic acid)-active compounds that exert beneficial effects. This review summarizes all information available on polyphenolic content and methods for their quantification in Chinese hawthorn berries and the relationships between individual polyphenolic compounds as well. The influence of species or cultivars, the locality of cultivation, the stage of maturity, and extract preparation conditions on the polyphenolic content were discussed as well. Currently, only fruits of C. pinnatifida and C. pinnatifida var. major are included in the Chinese Pharmacopoeia. Recent trials have demonstrated the efficacy of Chinese hawthorn fruit in lowering blood cholesterol and the risk of cardiovascular diseases. The fruit has also demonstrated anti-inflammatory and anti-tumour activities. This review deals mainly with the biological activity of the fruit related to its antioxidant properties.

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    • "Determination of biochemical compositions of edible wild species will allow the food industry to use such species as additives to develop new foodstuff. Information about their bioactive compounds will also let the consumers to know whether they can be used as direct foodstuff (Yilmaz et al. 2009;Jurikova et al. 2012). Modern objectives in plant breeding may be achieved by the evaluation of traits amongst genetic resources. "
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    • "Clinical evidence indicates that some hawthorn extracts may increase the exercise tolerance of patient with congestive heart failure [5]. The pharmacological effects were believed to mainly possess a number of beneficial effects such as cardiotonic [5], hypolipidemic [6] [7], and antioxidative activities [8]. Analytical results suggest that the procyanidins are the major active constituents in the Chinese hawthorn, which consists of epicatechin and procyanidin B2 [9]. "
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