Article

Prevalence of depression in adults with cancer: A systematic review

Psychological Medicine Research Department of Psychiatry, University of Oxford, Oxford.
Annals of Oncology (Impact Factor: 7.04). 11/2012; 24(4). DOI: 10.1093/annonc/mds575
Source: PubMed

ABSTRACT

Background
Depression has substantial effects on cancer patients' quality of life. Estimates of its prevalence vary widely. We aimed to systematically review published studies to obtain the best estimate of the prevalence of depression in clinically meaningful subgroups of cancer patients.DesignSystematic review that addressed the limitations of previous reviews by (i) including only studies that used diagnostic interviews; (ii) including only studies that met basic quality criteria (random or consecutive sampling, ≥70% response rate, clear definition of depression caseness, sample size ≥100); (iii) grouping studies into clinically meaningful subgroups; (iv) describing the effect on prevalence estimates of different methods of diagnosing depression.ResultsOf 66 relevant studies, only 15 (23%) met quality criteria. The estimated prevalence of depression in the defined subgroups was as follows: 5% to 16% in outpatients, 4% to 14% in inpatients, 4% to 11% in mixed outpatient and inpatient samples and 7% to 49% in palliative care. Studies which used expert interviewers (psychiatrists or clinical psychologists) reported lower prevalence estimates.Conclusions
Of the large number of relevant studies, few met our inclusion criteria, and prevalence estimates are consequently imprecise. We propose that future studies should be designed to meet basic quality criteria and employ expert interviewers.

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    • "Σε αυτές επισημαίνεται ότι η εντατική φροντίδα είναι πιο αποτελεσματική από την πρότυπη φροντίδα στη μείωση των καταθλιπτικών συμπτωμάτων. Ενώ φαίνεται λογικό να θεραπεύεται η κατάθλιψη σε άτομα με καρκίνο του πνεύμονα με τις πρότυπες θεραπείες έως ότου γίνουν διαθέσιμες πιο συγκεκριμένες ενδείξεις, οι κλινικοί γιατροί πρέπει να γνωρίζουν ότι η αποτελεσματικότητα και οι πιθανές δυσμενείς επιπτώσεις από αυτές τις θεραπείες παραμένουν άγνωστες σε αυτούς τους ασθενείς (Walker et al., 2013). ΣΥΜΠΕΡΑΣΜΑΤΑ Ο καρκίνος του πνεύμονα είναι η δεύτερη συχνότερη μορφή καρκίνου και η κύρια αιτία θανάτου από καρκίνο και στα δύο φύλα. "
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    • "Los resultados obtenidos en estudios en los que se han aplicado intervenciones propuestas para mejorar el bienestar espiritual muestran respuestas importantes en desenlaces clínicos (Breitbart et al., 2010; Kissane, et al., 2003; Lee, Cohen, Edgar, Laizner, & Gagnon, 2006; Spiegel, Bloom, & Yalom, 1981). Por lo tanto, dados estos resultados se espera que la intervención propuesta aquí, además de fomentar la espiritualidad de los pacientes, ayude a disminuir los niveles de depresión, ansiedad y malestar psicológico y espiritual asociados al tratamiento (Fann, et al., 2008; Galloway, et al., 2012; Hegel, et al., 2006; Neilson, et al., 2012; Reich, Lesur, & Perdrizet-Chevallier, 2008; Vehling, et al., 2012; Walker, et al., 2012; Moadel, et al., 1999; Nathan Cummings Foundation, Fetzer Institute, & George H. Gallup International Institute, 1997; Nixon & Narayanasamy, 2010; Okon, 2005) y a mejorar la calidad de vida. Dado que la prueba piloto fue realizada en un grupo de pacientes con variables socioculturales y clínicas muy limitadas, podría ser necesario adaptar el lenguaje para pacientes con otro tipo de características , por ello es importante que esta sea dirigida por un psicólogo clínico con la experiencia necesaria para adaptarse al contexto y las características de cada grupo. "
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