Management of Acute Bleeding from a Peptic Ulcer

Department of Gastroenterology and Gastrointestinal Outcomes Unit, Rambam Health Care Campus and Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel.
New England Journal of Medicine (Impact Factor: 55.87). 09/2008; 359(9):928-37. DOI: 10.1056/NEJMra0706113
Source: PubMed
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Available from: Marc Bardou
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    • "The use of prokinetics before endoscopy should be considered in selected patients. Meta-analyses have shown that erythromycin led to decreased need for repeat endoscopy[26], but failed to change the length of stay (LOS), transfusion requirements and need for surgery[27,28]. Data in variceal bleeding however demonstrate improved visibility, decreased duration of endoscopy and LOS with erythromycin given 30 minutes prior to endoscopy performed within 12 hours of presentation[29]. "

    Preview · Article · Jan 2015 · Journal of Gastroenterology and Hepatology Research
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    • "Discussion UGIB is a common cause of hospital visits and admissions, at a cost estimated as US$2.5 billion annually [Albeldawi et al. 2010]. It carries a mortality of up to 10% [Gralnek et al. 2008]. "
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    ABSTRACT: Background: Upper gastrointestinal bleeding (UGIB) accounts for 400,000 hospital admissions in the US each year. Despite advances, mortality rates remain high and are estimated to be 5–10%. Early therapeutic endoscopy is widely recommended as a means of reducing morbidity and mortality. The Rockall and Blatchford scores are clinical scoring systems devised to assist in risk stratifying patients with UGIB. In a prior study we found that rapid live bedside video capsule endoscopy (VCE) utilizing Pillcam ESO® correctly identified patients with high-risk stigmata of bleeding seen on upper endoscopy. In this study, we compare the accuracy of the Rockall and Blatchford scores with Pillcam ESO® in predicting high-risk endoscopic stigmata.
    Full-text · Article · May 2013 · Therapeutic Advances in Gastroenterology
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    • "The natural history of ulcer disease shows a rebleeding rate of approximately 5% only in the case of Forrest type IIc or III (Table 4) [44]. "
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    ABSTRACT: Intensivists are regularly confronted with the question of gastrointestinal bleeding. To date, the latest international recommendations regarding prevention and treatment for gastrointestinal bleeding lack a specific approach to the critically ill patients. We present recommendations for management by the intensivist of gastrointestinal bleeding in adults and children, developed with the GRADE system by an experts group of the French-Language Society of Intensive Care (Societe de Reanimation de Langue Francaise (SRLF), with the participation of the French Language Group of Paediatric Intensive Care and Emergencies (GFRUP), the French Society of Emergency Medicine (SFMU), the French Society of Gastroenterology (SNFGE), and the French Society of Digestive Endoscopy (SFED). The recommendations cover five fields of application: management of gastrointestinal bleeding before endoscopic diagnosis, treatment of upper gastrointestinal bleeding unrelated to portal hypertension, treatment of upper gastrointestinal bleeding related to portal hypertension, management of presumed lower gastrointestinal bleeding, and prevention of upper gastrointestinal bleeding in intensive care.
    Full-text · Article · Nov 2012 · Annals of Intensive Care
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