Hepatitis A among International Adoptees and Their Contacts

Viral Hepatitis, STD and TB Prevention, National Center for HIV/AIDS, Detection and Control of Infectious Diseases, Centers for Disease Control, Atlanta, Georgia 30333, USA.
Clinical Infectious Diseases (Impact Factor: 8.89). 10/2008; 47(6):812-4. DOI: 10.1086/591199
Source: PubMed


We identified 27 cases of hepatitis A among international adoptees (5 persons), their direct or indirect contacts (20 persons),
and unvaccinated travelers to the adoptees' countries (2 persons). Most cases occurred among nontraveling contacts of adoptees,
suggesting the need to extend prevention guidelines to include hepatitis A vaccination for at-risk nontravelers.

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    • "However, foodborne outbreaks [3] have occurred, for example, after ingestion of shellfish living in sewage-polluted waters [4] or through contaminated vegetable salads [5]. In addition, HAV infection may occur in individuals or groups with high risk of infection, such as travellers to areas of high endemicity [6], men who have sex with men [7], intravenous drug users, and in other specific subpopulations [8]. A substantial proportion of adolescents and adults are susceptible in most developed countries. "
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    ABSTRACT: In a background of very low incidence of hepatitis A HA in the last decade (annual average of 1.8 cases per 100,000 inhabitants) we describe an outbreak of HA which evolved in Mallorca between May and August 2010, whose main focus was a nursery school where more cases were parents and other young relatives of the children of the institution. Thirty-four cases were defined as outbreak cases. Ten were children of the nursery or their siblings and 22 adults (3 staff members of the nursery and 19 relatives; median age 33 years). The first detected cases were children of the same class. There were 2 adults with haematological complications, though not severe. All children, nursery staff members, parents, and siblings of the cases of the first affected class were immediately offered HA vaccination, but only 43.3% eligible individuals accepted it. None of the cases had been vaccinated. The outbreak spread mostly from asymptomatic children to young adults, showing the changes in HA pattern. That is of great concern as the risk of severe illness rises with age. This incident shows the need to implement new HA vaccination policies in outbreak control. This was later carried out.
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