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3D ultrasound-guided motion compensation for intravascular radiation therapy
... As a consequence, very precise localisation of the pulmonary veins and compensation of both respiratory and pulsatory motion is required. That the detection of the pulmonary veins using live 3D ultrasound actually is possible has been demonstrated [20,21]. Furthermore, the application of algorithms developed with the goal of human respiratory motion prediction to pulsatory motion will be investigated in section 4. 6. Apart from this novel approach, there also is a limited number of patients who actually suffer from cardiac cancer [188] or tumours which move with pulsation [191]. ...
Compensating for Quasi-periodic Motion in Robotic Radiosurgery outlines the techniques needed to accurately track and compensate for respiratory and pulsatory motion during robotic radiosurgery. The algorithms presented within the book aid in the treatment of tumors that move during respiration. In Chapters 1 and 2, the book introduces the concept of stereotactic body radiation therapy, motion compensation strategies and the clinical state-of-the-art. In Chapters 3 through 5, the author describes and evaluates new methods for motion prediction, for correlating external motion to internal organ motion, and for the evaluation of these algorithms’ output based on an unprecedented amount of real clinical data. Finally, Chapter 6 provides a brief introduction into currently investigated, open questions and further fields of research. Compensating for Quasi-periodic Motion in Robotic Radiosurgery targets researchers working in the related fields of surgical oncology, artificial intelligence, robotics and more. Advanced-level students will also find this book valuable.
This chapter describes the principles of motion compensation in radiotherapy with a focus on robotic radiosurgery, starting with a brief description of the medical implications. Throughout, special emphasis will be placed on the CyberKnife_R system and we will outline the problems originating from the aim of real-time motion compensation. The main current application of robotic radiotherapy is the treatment of malignant tumours while a second, very promising field is the therapy of cardiac arrhythmia, especially of atrial fibrillation. An outline of this project called CyberHeart, and the challenges emanating from it, will be given in section 2.5.a
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