Malignant Rhabdoid Tumor of the Lung in the Young Adult: A Case Report

Pulmonology Department, King Fahad Specialist Hospital, Damman 31444, Saudi Arabia.
Case reports in pulmonology 10/2011; 2011(7):323584. DOI: 10.1155/2011/323584
Source: PubMed


Malignant rhabdoid tumor (MRT) is one of the most aggressive and lethal malignancies in pediatric oncology. Malignant rhabdoid tumor was initially described in 1978 as a rhabdomyosarcomatoid variant of a Wilms tumor because of its occurrence in the kidney and because of the resemblance of its cells to rhabdomyoblasts. The absence of muscular differentiation led Haas and colleagues to coin the term rhabdoid tumor of the kidney in 1981, Haas et al..

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    • "Extra renal rhabdoid tumors have been described in the liver, brain, tongue, neck, chest, heart, pelvis, extremities, and several other sites. Three reports have highlighted rhabdoid differentiation in the lung tumours; however, it has not been described as endoluminal growth in the trachea [3] [4] [5]. "
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    ABSTRACT: Rhabdoid tumours are one of the most aggressive childhood neoplasms associated with high mortality. The commonest age group affected is children less than five years of age. Rhabdoid tumour presenting as an endoluminal tracheal mass leading to central airway obstruction has not been previously reported. We describe the case of a 17-year-old male patient where malignant rhabdoid tumour masqueraded as bronchial asthma leading to a delayed diagnosis of upper airway obstruction by tracheal growth. Histopathological examination and immunohistochemistry confirmed the diagnosis of malignant rhabdoid tumour.
    Full-text · Article · Aug 2014