Granular Cell Tumor of Skin Diagnosed on Fine Needle Aspiration Cytology

Institute of Pathology ICMR, New Delhi, India.
Indian Journal of Dermatology 07/2012; 57(4):330-1. DOI: 10.4103/0019-5154.97690
Source: PubMed
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    ABSTRACT: Granular cell tumors (GCT) are uncommon tumors of uncertain histogenesis. They may occur at any site and most commonly involve the tongue, breast, upper respiratory tract, and soft tissue of upper extremities; however, the involvement of skin is rare. The cytological findings of cutaneous GCT are limited to a few cases being reported till date; we report a case of cutaneous granular cell tumor in a 42-year-old male.
    No preview · Article · Oct 2013 · Journal of Cytology
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    ABSTRACT: This case report describes the use of fine needle aspiration cytology to diagnose a granular cell tumour (GCT) that presented as a painless, palpable mass at the abdominal wall in a 50-year-old woman who had had the mass for ≥1 year prior to presentation. Routine haematoxylin and eosin staining of the cytological smears demonstrated that the specimen was predominantly cellular; it contained both cell clusters and single cells with abundant granular cytoplasm and indistinct cell borders. Cells were fragile and had fairly uniform naked nuclei that were scattered with vacuolated and prominent nucleoli. Background material on the smears included eosinophilic, granular cytoplasmic material and some adipose tissue. Neither mitoses nor necrosis were observed. A cytological diagnosis of a GCT was confirmed by histological examination of a surgical specimen stained with haematoxylin and eosin. This case report found that the GCT had a characteristic cytological appearance and that cells with prominent nucleoli can be present in benign GCTs. © The Author(s) 2015 Reprints and permissions:
    No preview · Article · May 2015 · The Journal of international medical research