Sebaceous gland melanosis in dogs with endocrine skin disease or follicular dysplasia: A retrospective study
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853–6401, USA Veterinary Dermatology
(Impact Factor: 1.73).
06/2008; 7(2):85 - 90. DOI: 10.1111/j.1365-3164.1996.tb00231.x
Skin biopsy specimens from 107 dogs with endocrine skin disorders were examined for the presence of melanin granules in the sebaceous glands or ducts (sebaceous gland melanosis). Nineteen of these cases (17.8%) had sebaceous gland melanosis. Skin biopsy specimens from 71 dogs with follicular dysplasia were similarly examined and 27 (38.0%) had sebaceous gland melanosis. Sebaceous gland melanosis alone cannot be used to differentiate histologically follicular dysplasia and endocrine skin disorders.
Available from: biblio.ugent.be
- "The size of the adnexae is normal , but sebaceous glands may be melanized. Melanin aggregates may also be present in the follicular lumen (Bagladi et al., 1996;Miller and Dunstan, 1993). The timing of the biopsies greatly influences the histopathological changes (Gross et al., 2005d;Paradis, 2009). "
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ABSTRACT: Canine recurrent flank alopecia is a non-inflammatory, non-scarring alopecia of unknown etiology and has a visually striking clinical presentation. Although this disease entity is relatively common in the northern hemisphere, there is only scant information in the literature regarding case descriptions. The aim of this article was to review the literature and to describe clinical presentations recognized in practice, which are not always extensively documented in the literature.
Available from: oatao.univ-toulouse.fr
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