Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms Reply

ArticleinNew England Journal of Medicine 367(3):248-57 · July 2012with11 Reads
Impact Factor: 55.87 · DOI: 10.1056/NEJMcp1106637 · Source: PubMed


    A 59-year-old man with a history of benign prostatic hyperplasia and lower urinary tract symptoms comes for care. He has been receiving doxazosin at a dose of 4 mg daily (his only medication) for the past 2 years, with minimal improvement. He continues to have nocturia, a weak urinary stream, and urinary frequency (voiding eight times per day). How would you manage this case?