A Synthetic Route to Anandamide Analogues Carrying a Substituent at the Terminal Carbon and an Acetylene Group in the End Pentyl Chain

ArticleinTetrahedron Letters 45(28):5449-5451 · November 2004with8 Reads
Impact Factor: 2.38 · DOI: 10.1016/j.tetlet.2004.05.071

    Abstract

    A versatile sequence is developed for the synthesis of anandamide analogues with an acetylene group in the end pentyl chain carrying a substituent at the terminal carbon of the chain. These analogues are important for SAR studies of the endocannabinoid, anandamide.