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A Review on Medicinal Properties of Lantana camara Linn

ABSTRACT

The knowledge of traditional medicine and medicinal plants and their study of scientific chemical principles may lead to the discovery of newer and cheaper drugs. Lantana camara is well known to cure several diseases and used in various folk medicinal preparations. In last few decades, scientist and researchers around the globe have elaborately studied the chemical composition of whole plant of L. camara as well as biological pharmacological activities. These studies established the therapeutic potential of Lantana camara in modern medicines and a possible candidate for the drug discovery. The present review gives a bird's eye view on ethnobotany, phytochemistry, pharmacology and toxicology of L. camara.

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    • "In Nigeria, L. camara has as local names " Ewonadele " in Yoruba, " Kimbamahalba " in Hausa, and " Anya nnunu " in Igbo (Gabi et al. 2011). According to Sanjeeb et al. (2012), the plant is said to have antibacterial, antifungal, wound healing, antimotility, antiulcerogenic, hemolytic, antihyperglycemic, antifilarial , antiinflammatory, embryo toxicity, antiurolithiatic, anticancer and antiproliferative, antimutagenic, antioxidant, and mosquitoescontrolling activities. In this work, we investigated the single and combined repellent actions using the methanol crude extract (MCE), hexane fraction (HF), and ethyl acetate fraction (EAF) from O. gratissimum and L. camara against Ae. "
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    ABSTRACT: Mosquitoes are the most deadly vectors of parasites that cause diseases such as malaria, yellow fever, and filariasis. In view of the recent increased interest in developing plant origin insecticides as an alternative to chemical insecticides, the objective of this study was to determine the repellent activity of creams formulated with methanol crude extract (MCE), hexane fraction (HF), and ethyl acetate fractions (EAFs) of Ocimum gratissimum and Lantana camara leaves in single and combined actions against female Aedes aegypti. Evaluation was carried out in the net cages (30 by 30 by 30 cm) containing 60 blood-starved female mosquitoes each and were assayed in the laboratory condition following World Health Organization 2009 protocol. All formulations (single and mixture) were applied at 2, 4, 6, and 8 mg/cm(2) in the exposed area of human hands. Only acetone + white soft paraffin served as negative control and odomos (12% DEET) as positive control. All the formulations presented good protection against mosquito bites without any allergic reaction by the human volunteers. The repellent activity was dependent on the strength of the extracts and fractions. Among the tested formulations, the maximum protection time was observed in MCE (120 min) and EAF (150 min) of O. gratissimum; MCE:MCE (150 min) and HF:HF (120 min) mixtures of both plants. In addition, MCE:MCE and HF:HF mixtures from both plants showed possible synergistic effect. From the results, the combination of O. gratissimum and L. camara to formulate natural mosquito repellent using small amount of extracts can be encouraging to be an alternative to conventional DEET. © The Author 2015. Published by Oxford University Press on behalf of the Entomological Society of America.
    Full-text · Article · Apr 2015 · Journal of Insect Science
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    Full-text · Article · Oct 2013 · International Journal of Biological and Chemical Sciences
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    ABSTRACT: Diabetes mellitus is a metabolic disorder characterized by hyperglycemia, hyperlipidemia, hyperaminoacidemia, and hypoinsulinaemia which leads to reduce in both insulin secretion and insulin action. It is often connected with the development of micro and macro vascular diseases which include a long term damage, dysfunction and failure of various organs especially the eye, nerves, heart, kidney and blood vessels. Various approaches have been developed for the treatment of diabetes, like insulin management and use of a variety of oral hypoglycemic agents but these synthetic drugs are costly and often associated with high chances of side effects. A wide number of medicinal plants are described in Ayurveda and traditional medicinal system which are used for the treatment of diabetes from ancient time. The present paper is an attempt to represent the list of the anti-diabetic plants, and their active constituents with a particular mechanism of action. The active principles present in medicinal plants have been reported to possess various activities such as pancreatic beta cell regeneration, stimulating insulin release, showing insulin-like action, fighting the problem of insulin resistance, and reducing the uptake, absorption and utilization of glucose. The recent development of herbal formulations for the treatment of diabetes include using combined extracts of the different plants or different parts of the same plants; development of novel targeted drug delivery systems etc. Perceived effectiveness, fewer side effects, controlled rate of drug release and targeted approaches are the recent areas of herbal technological developments.
    Full-text · Article · Jan 2014
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Questions & Answers about this publication

  • Renata Baczek-Kwinta asked a question in Lantana:
    What about invasiveness?
    Such an interesting plant! Have you considered its impact on the environment? I know thal Lantana species can be invasive.
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      [Show abstract] [Hide abstract]
      ABSTRACT: The knowledge of traditional medicine and medicinal plants and their study of scientific chemical principles may lead to the discovery of newer and cheaper drugs. Lantana camara is well known to cure several diseases and used in various folk medicinal preparations. In last few decades, scientist and researchers around the globe have elaborately studied the chemical composition of whole plant of L. camara as well as biological pharmacological activities. These studies established the therapeutic potential of Lantana camara in modern medicines and a possible candidate for the drug discovery. The present review gives a bird's eye view on ethnobotany, phytochemistry, pharmacology and toxicology of L. camara.
      Full-text · Article · Jul 2012 · Research Journal of Pharmacy and Technology