In this paper, we explore the issues related to creating, integrating and maintaining multiple local ontologies, and how and whether a global reference ontology can be of use. We note that a major problem in existing organizations is the lack of consistent terminology. The adoption of a global reference vocabulary or ontology seems an attractive solution in theory, but in practice, this approach seems untenable. We believe that a mixed approach which enables local groups to build maintain and use their own ontologies, in conjunction with a global reference ontology, and mapping between them is a more viable approach. We describe various issues and approaches that arise in attempting to do this.