The movable type printing press was the signal innovation in early modern information technology, but economists have found no evidence of its impact in measures of aggregate productivity or income per person. This paper exam-ines the technology from a new perspective by exploiting city-level data on the establishment of printing presses in 15th century Europe. I find that between 1500 and 1600, cities where printing presses were established in the late 1400s grew at least 60 percent faster than similar cities which were not early adopters. Between 1500 and 1800, print cities grew at least 25 percent faster. I show that cities that adopted printing had no prior advantage and that the association between adoption and subsequent growth was not due to printers anticipat-ing city growth or choosing auspicious locations. My findings imply that the diffusion of printing accounted for between 20 and 80 percent of city growth 1500-1600 and between 5 and 45 percent of city growth 1500-1800. They are supported by analysis using OLS, propensity scoring methods, difference-in-difference estimators, and IV regressions that exploit distance from Mainz, the birth place of printing, as an instrument for early adoption. Historical evidence confirms that the printing press greatly reduced the costs of transmitting com-plex information between cities, but was associated with localized spillovers in human capital accumulation and technological change. for discussions. The errors are mine.