Social inclusion in science is a complex issue. During the past decades, research centres, science centres, museums and other institutions invested in science communication aiming to promote cultural activities to diverse audiences. Despite this investment, science communicators from all over the world face the same challenge: how to reach citizens that are not interested in science? The main goals for this project were to explore innovative techniques to engage socially-vulnerable communities with science, and propose a model of science communication built on this practice-based research. The project, named “Embodying Memories”, was developed in a collaborative way between science partners (IGC - Instituto Gulbenkian de Ciência, iNOVA Media Lab), art partners (museum from FCG – Fundação Calouste Gulbenkian) and administrative partners (Câmara Municipal de Oeiras). The target audience, a senior community of women, most illiterate and migrant from Africa, was involved on the project plan since early stages, starting with the topic choice - Memory. The project implementation consisted of eight sessions that took place over a period of more than two months in 2018, covering several themes related to memory and brain. Diverse formats were used for the session’s activities, from scientific presentations, neuroscience stories or study cases, community memories sharing, to more interactive activities stimulating body movement, abstraction and self-expression. Besides in-door sessions at the migrant support centre, a visit to the FCG museum and a visit to IGC laboratories were organized, and a project public presentation was performed. The project was qualitatively evaluated to identify changes in awareness, knowledge, engagement, attitude and social inclusion, which was made by the analysis of field notes, attendance record, pre/post assessment focus group, community project evaluation, project narrative, and public presentation content. Overall, it was considered that the project had a moderate achievement, from a balance between very high attendance and willingness to participate in new cultural experiences, high engagement with the project, moderate increase in knowledge about neuroscience, and some increase in awareness and engagement with science, stimulation of curiosity, abstraction and self-expression. To achieve a high level of engagement, a dynamic equilibrium was constantly in a trial between the six axes of the project (science education, art education, cultural entertainment, social inclusion, mental health promotion, institutional advertising), and respective institutions. The most important project achievements were the fluidity and fruition of the project itself, and the opportunity given to participants to engage with Science & Art, to visit the museum and laboratories, to meet scientists and science instruments. A relevant asset of the project, was the existence of the boundary spanner, which was developed along pre- and during sessions by taking actions, visits, share experiences and events to inhabit the laboratory sphere, the museum sphere, and the community world. The role of the boundary spanner was crucial, yet challenging to balance between how much would be desirable for each partner to stay in and out of their comfort zones and territories. Based on insights gained from the project development and evaluation, a model was proposed to guide science communication projects using Science & Art approaches to promote social inclusion. The model entails the following phases: Phase 1. Design, plan and collaboration; Phase 2. Implementation; and Phase 3. Evaluation.