The diagnosis and management of syphilis in the HIV-infected patient

ArticleinCurrent Infectious Disease Reports 2(1):10-13 · April 2012with17 Reads
Impact Factor: 1.68 · DOI: 10.1007/s11908-000-0081-1


    In the 1980s, the number of cases of syphilis in the United States increased concurrently with the onset of the HIV epidemic.
    Within a short time, clinicians began to note unusual presentations of syphilis and inappropriate responses to standard therapy
    for syphilis in dually infected patients. Whether these cases collectively represented a new aspect of the natural history
    of syphilis remains to be elucidated. In recent years, only a few prospective studies have addressed this issue, and the results
    of these studies have been inconclusive.