Computational modelling of morphological development of tissues based on complex systems and cellular automata can be decomposed into three interdependent processes. Those three crucial parts are mechanical response of tissues, diffusion of signalling molecules, and gene regulatory network. It is shown that development of an adequate mechanical model of living tissues provides the morphological model with sufficient flexibility necessary to achieve expected morphological development scenarios. In this contribution, the attention is focussed to development of mesenchymal and epithelial tissues which, e.g., creates the
basic mechanism of tooth development. The future development of the model is discussed with emphasis on open questions.
Link to the book chapter: