Bronquiolitis obliterante con neumonía organizada: forma poco frecuente de toxicidad pulmonar en el tratamiento radioterápico del cáncer de mama

Clinical and Translational Oncology (Impact Factor: 2.08). 6(4):239-241. DOI: 10.1007/BF02711728


The incidence of symptomatic pneumonitis in patients who had received radiation therapy for breast cancer is low (<1%). Recently,
bronchiolitis obliterans organizing pneumonia (BOOP) syndrome has been described as a secondary lung toxicity due to the radiation
therapy, which appears beyond the radiation field (migratory pneumonitis) and is triggered by hypersensitivity reactions mediated
by eosinophils, neutrophils and lymphocytes.

We present a patient who, two months after concluding the scheduled radiotherapy, developed a set of clinical, pathological
and radiological symptoms compatible with BOOP syndrome. The patient responded well to steroid treatment.

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