Article

[Adaptive changes in succinate dehydrogenase activity in different functional states of rat kidney]

Article

[Adaptive changes in succinate dehydrogenase activity in different functional states of rat kidney]

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Article
Isoenzyme spectra of cytoplasmic muscle malate dehydrogenase (MDG) from ten sturgeon species inhabiting the territory of the Commonwealth of Independent States were studied by disc-electrophoresis in 7% polyacrylamide gel. It was found that in sturgeons, MDG is characterized by a high heterogeneity and polymorphism. The MDG spectra are suggested to be of unequal evolutionary value under different ecological conditions. The hypothesis on the advantages of one of the MDG phenotypes when living in fresh water with no possibility of migrations to salty reservoirs during feeding is discussed. This hypothesis is confirmed by analysis of changes in ecological conditions at the sites of formation of modern sturgeon populations from the Tertiary period to the present time. Possible ways of participation of MDG in maintaining the water-salt homeostasis are discussed.
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