Custard Apple and Latex Allergy: A New Type of Cross-reaction?
Available from: Yeldur Venkatesh
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ABSTRACT: Plant allergens, being one of the most widespread allergenic substances, are hard to avoid.
Hence, their identification and characterization are of prime importance for the diagnosis and
treatment of food allergy. The reported allergies to fruits mainly evoke oral allergy syndrome
caused by the presence of cross-reactive IgE to certain pollens and thus, allergy to fruits has
also been linked to particular pollens. Many fruit allergies are being studied for their causative
allergens, and are being characterized. Some tropical or exotic fruits are responsible for
region-specific allergies for which only limited information is available, and generally lack
allergen characterization. From a survey of the literature on fruit allergy, it is clear that some
common fruits (apple, peach, musk melon, kiwi fruit, cherry, grape, strawberry, banana, custard
apple, mango and pomegranate) and their allergens appear to be at the center of current
research on food allergy. The present review focuses on common fruits reported as allergenic
and their identified allergens; a brief description of allergens from six rare/tropical fruits is
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