Hemoglobin concentration increment is associated with a better prognosis in HIV patients with anemia

Article (PDF Available)inInternational journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases 16(9):e703 · June 2012with31 Reads
DOI: 10.1016/j.ijid.2012.04.008 · Source: PubMed
  • [Show abstract] [Hide abstract] ABSTRACT: HIV patients infected through injected drug use have poorer prognosis than other groups. We evaluated the hematological alterations and rates of co-infections in injected drug use patients with AIDS. Injected drug use patients were younger, predominantly of male gender, and presented lower CD4, total lymphocyte, and platelet counts, but not neutrophil count, than control group. Injected drug use patients had a higher rate of hepatitis C and mycobacteria infection. Furthermore, all injected drug use patients with hemoglobin <10.0gdL(-1) and lymphocyte <1000μL(-1) had CD4 count lower than 100μL(-1). In conclusion, HIV-infected injected drug use patients constitute a special group of patients, and hemoglobin concentration and lymphocyte count can be used as surrogate markers for disease severity.
    Full-text · Article · Aug 2013