Prevalence of albuminuria and associated cardiovascular risk factors: A community cohort in Namwon City, Korea

Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, South Korea.
Diabetes research and clinical practice (Impact Factor: 2.54). 06/2012; 97(3):492-8. DOI: 10.1016/j.diabres.2012.05.018
Source: PubMed


To document the prevalence of albuminuria and determine its relationship to risk factors for cardiovascular disease (CVD) among Korean adults.
We performed a cross-sectional study of adults aged 45-74 years from Namwon City, South Korea. Albuminuria was defined as a urinary albumin-to-creatinine ratio (UACR)≥30mg/g. The values of UACR were categorized into 5 groups: <10, 10-19, 20-29, 30-299, and ≥300mg/g. Risk factors for CVD and the estimated glomerular filtration rate (eGFR) were analyzed for an association with UACR values.
Data were obtained from 10,534 participants (4140 men and 6394 women). Albuminuria was more prevalent among women than men (27.3% versus 22.7%, respectively, p<0.001), and it was also more prevalent among older participants (p<0.001). The prevalence of albuminuria was 36.3% among participants with hypertension or type 2 diabetes, and it was 16.6% among participants without these conditions. The UACR was positively associated with CVD risk factors, including blood pressure, obesity indexes, total cholesterol, and the eGFR.
The prevalence of albuminuria is high in the general population in Korea, even among Koreans without CVD risk factors. Lower UACR values are associated with reduced CVD risk factors.

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