Basidiobolomycose probable chez un jeune rural togolais traitée avec succès par du kétoconazole

Bulletin de la Société de pathologie exotique 12/2010; 103(5):293-295. DOI: 10.1007/s13149-010-0090-8


La basidiobolomycose est une mycose profonde qui atteint préférentiellement les jeunes ruraux en zone tropicale. Nous rapportons
un cas de basidiobolomycose traité avec succès par du kétoconazole. Il s’agissait d’un garçon de 9 ans d’origine rurale chez
qui le diagnostic de basidiobolomycose était évoqué devant un placard infiltré de l’hémithorax droit et de la face latérale
droite du cou. L’histologie mettait en évidence une inflammation granulomateuse de siège dermohypodermique à prédominance
de macrophages et de polynucléaires éosinophiles. L’enfant était traité avec succès par du kétoconazole en huit semaines.
Le traitement de la basidiobolomycose est basé sur les dérivés azolés qui sont très efficaces. L’histologie occupe une place
importante dans le diagnostic de cette affection, surtout en zone tropicale où elle peut simuler une infection à Mycobacterium ulcerans.

Basidiobolomycosis is a deep mycosis which preferentially affects rural young people in tropical countries. We report a case
of basidiobolomycosis successfully treated with ketoconazole. It was a 9-year-old boy of rural origin in whom the diagnosis
of basidiobolomycosis was suspected due to a deep skin infiltration involving the chest and neck. Histology revealed hypodermic
granulomatous inflammation with predominantly macrophage and eosinophils. The child was treated successfully with ketoconazole
in eight weeks. Treatment of basidiobolomycosis is based on azole derivatives which are particularly effective. Histopathology
is very important in the diagnosis of this affection, especially in tropical countries where it may simulate Mycobacterium ulcerans infection.

Mots clésBasidiobolomycose–Kétoconazole–Enfant–Hôpital–Lomé–Togo–Afrique intertropicale
KeywordsBasidiobolomycosis–Ketoconazole–Child–Hospital–Lomé–Togo–Sub-Saharan Africa

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Available from: Koffi Amégbor, Dec 21, 2013
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