Detection of Intraluminal Tracheal Metastasis of Thyroid Papillary Carcinoma by F-18-FDG PET/CT

ArticleinClinical nuclear medicine 37(6):e160-1 · June 2012with9 Reads
DOI: 10.1097/RLU.0b013e318248515e · Source: PubMed
Abstract
We present a case of a 66-year-old female patient with thyroid papillary carcinoma. On the fluorine-18 fluorodeoxyglucose (F18-FDG) positron emission tomography/computed tomography (PET/CT) performed for thyroglobulin elevation accompanied by negative radioiodine whole-body scan, there was an intense 18F-FDG uptake in the polypoid soft tissue invading the tracheal cartilage and extending into the lumen. Dedifferentiated tumor with high metabolic rate can be easily detected by 18F-FDG PET/CT.
    • "The most common primary cancers associated with such metastases are breast and colon, although other tumors have also been described. Thyroid malignancy with endotracheal spread has rarely been reported in literature [5]. Patterns of tracheal metastases have been classified by Kiryu et al. [6]. "
    [Show abstract] [Hide abstract] ABSTRACT: Endotracheal metastasis is a rare situation, usually associated with malignancies of breast and gastrointestinal tract, specially colon. Papillary carcinoma of thyroid commonly disseminates through lymphatic channels and tracheal involvement through vascular route is rarely reported. Here, we report a case of tracheal metastasis from papillary carcinoma of thyroid. The patient responded to external beam radiation therapy with cobalt 60 beams in a dose of 44 Gy followed by a 16 Gy boost. The patient is under followup and is presently asymptomatic. This paper adds to the repertoire of evidence in treatment of endotracheal metastasis.
    Full-text · Article · Oct 2012
  • [Show abstract] [Hide abstract] ABSTRACT: Endotracheal infiltration by lymphoma is uncommon. We present 2 cases of endotracheal infiltration by non-Hodgkin lymphoma. One case had a solitary lesion in the middle trachea. Bronchoscopic biopsy of the lesion revealed diffuse large B-cell lymphoma. The tumor showed focal FDG uptake with SUVmax of 15. The other case had diffuse endotracheal lesions. Bronchoscopic biopsy revealed diffuse submucosal infiltration by natural killer/T-cell lymphoma. The thickened trachea showed diffuse FDG uptake with SUVmax of 8.4. These 2 cases indicate lymphoma should be included in the differential diagnosis of focal or diffuse endotracheal FDG accumulation.
    Article · Nov 2013