Dexmedetomidine in a Child with Methylphenidate Intoxication

ArticleinThe Indian Journal of Pediatrics 80(4) · May 2012with11 Reads
Impact Factor: 0.87 · DOI: 10.1007/s12098-012-0757-1 · Source: PubMed


    Methylphenidate intoxication, due to accidental ingestion, is a common occurrence in pediatrics. Symptoms of extreme agitation are typically controlled with benzodiazepines or barbiturates. There is, however, a legitimate risk of mechanical ventilation due to respiratory depression with increasing doses of benzodiazepines. The authors describe a case of 7-y-old girl with methylphenidate toxicity where dexmedetomidine was successfully used to manage agitation and cardiovascular stimulation without respiratory compromise.