Article

Immunoglobulin A Nephropathy Associated with Plasmodium falciparum Malaria

Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Journal of Korean medical science (Impact Factor: 1.27). 04/2012; 27(4):446-9. DOI: 10.3346/jkms.2012.27.4.446
Source: PubMed

ABSTRACT

Glomerulonephritis occurs as a rare form of renal manifestation in Plasmodium falciparum malaria. Herein, we report a case of falciparum malaria-associated IgA nephropathy for the first time. A 49-yr old male who had been to East Africa was diagnosed with Plasmodium falciparum malaria. Microhematuria and proteinuria along with acute kidney injury developed during the course of the disease. Kidney biopsy showed mesangial proliferation and IgA deposits with tubulointerstitial inflammation. Laboratory tests after recovery from malaria showed disappearance of urinary abnormalities and normalization of kidney function. Our findings suggest that malaria infection might be associated with IgA nephropathy.

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Available from: Yoonseon Park, May 19, 2015
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    • "To our best of knowledge, the only case suggesting the link between IgAN and P. falciparum infection was recently reported by Yoo et al. (16). They described a 49-year-old male who was diagnosed with P. falciparum malaria. "
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