Diagnostic de la tuberculose ganglionnaire périphérique en Tunisie

Laboratoire d’hygiène, CHU Hédi Chaker, Sfax, Tunisie
Médecine et Maladies Infectieuses (Impact Factor: 1.24). 02/2010; 40(2):119-122. DOI: 10.1016/j.medmal.2009.10.014


ObjectiveThe aim of the study was to evaluate the contribution of microbiology, cytology, and anatomopathology in 50 cases of peripheral tuberculous lymphadenitis.MethodologyOur patients underwent bacteriological tests and cytology and/or histopathology for lymphadenitis.ResultsZiehl-Neelsen stains and cultures were positive in only 29.7% and 10.8% of cases respectively. The diagnosis was confirmed by cytology in 31.3% of cases (10/32) and by histology in 58.6% of cases (27/46). Granulomas were observed in 46.8% (15/32) of needle aspirates and 76% (35/46) of surgical biopsies.ConclusionOur study reveals a weak contribution of conventional microbiological techniques. Cytology remains the procedure of choice in endemic countries. Excisional biopsy may be performed in case of doubt.

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    • "less effective than its counterpart reported in the same study [9]. Overall, the sensitivity of microbiological methods is considered mediocre and disparate. "
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    ABSTRACT: To evaluate patients’ profiles, demographics, clinical and therapeutic approaches and strategies in patients with tuberculous lymphadenitis (TBG).Patients and methodsA retrospective study of all TBG-confirmed cases admitted in a tuberculosis specific health care facility between 1 January 2009 and 16 June 2013.ResultsA total of 181 clinical files were examined. Mean age was 32 years old; the female/male ratio was 1.78 to 1. Raw milk consumption was noted in 1/3 of patients. Most cases involved the head and neck region (83.4%), nodes involvement, including axillary (12 cases), and mediastinal (9 cases). Clinical symptoms were present in only 55.2%. TST was conducted with 82.6% positive responses. Diagnostics confirmation was done with anatomical pathology in most of the patients; only 56 of them had any microbiology analysis done. Demonstration of acid-fast bacilli in microscopy from either fine-needle aspirates or biopsies was done in 17.5%, and cultures yielded positive results in 27%. Treatment duration was varied. Paradoxical reactions were noted in 12% and persistent lymphadenopathy after treatment completion was noted in 10% of cases.ConclusionsTBG remains a disease of interest. Today, its diagnosis and management is still a problem despite its increasing worldwide incidence, and especially in this study area. Disease control should be strengthened in this country.
    Full-text · Article · Nov 2014 · International Journal of Mycobacteriology
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    Full-text · Article · Jan 2014 · Pan African Medical Journal
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    No preview · Article · Aug 2014 · Revue de Pneumologie Clinique