Review Indian medicinal herbs as sources of antioxidants

Department of Biotechnology, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India
Food Research International (Impact Factor: 2.82). 12/2008; 41:1-15. DOI: 10.1016/j.foodres.2007.10.001


Currently there has been an increased interest globally to identify antioxidant compounds that are pharmacologically potent and have low or no side effects for use in preventive medicine and the food industry. As plants produce significant amount of antioxidants to prevent the oxidative stress caused by photons and oxygen, they represent a potential source of new compounds with antioxidant activity. Traditional herbal medicines form an important part of the healthcare system of India. Ayurveda, supposed to be the oldest medical system in the world, provides potential leads to find active and therapeutically useful compounds from plants. Considering the growing interest in assessing the antioxidant capacity of herbal medicine in this review we discuss about rarely reviewed 24 plants reported to have antioxidant properties. Some of the plants reviewed are part of multi-herbal preparations while others are used singly. Certain herbs like Amaranthus paniculatus, Aerva lanata, Coccinia indica and Coriandrum sativum are used as vegetables indicating that these plants could be source of dietary antioxidant supplies, which is another emerging area of research.

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    • "During the past decade, much research was devoted to try and establish the precise relationship between reactive oxygen species (ROS) and the development of various diseases such as cancer, arthritis and different kinds of cardiovascular problems , as well as the degenerative processes associated with aging, including Alzheimer and Parkinson diseases [12]. Recently , several epidemiological studies suggest that the consumption of fresh fruit, vegetables or different types of herbal infusion has protective effects against such diseases with the beneficial outcomes being attributed in part to the presence Table I "
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    ABSTRACT: Abstract – Introduction. Mexico harbors a great diversity of Spondias purpurea ecotypes, whose fruit is called Mexican plum and has a good consumer acceptance because of its organoleptic and nutritional characteristics. Materials and methods. The concentrations of metabolites in 11 ecotypes of Mexican plum were determined from samples of rind (epicarp) and pulp originating from fresh seasonal fruit. Results and discussion. The mass of these fruits varied from 11.1 to 35.0 g, and the epicarp color ranged from purple and red, to orange and yellow. The content of total soluble solids, total sugars, and vitamin C was of 9.4−18.2 ◦Brix, 101.0−185.9 mg g−1 fresh weight (FW), and 0.6−2.1 mg g−1 FW, respectively. The total phenolic content was always higher in the epicarp (3.7 mg g−1 FW) than in the pulp (1.3 mg −1 FW), as was the total content of carotenoids and the levels of antioxidant activity. Additionally, positive correlations could be established between antioxidant activity and total phenolics, total phenolics and total carotenoids, and between the antioxidant activity in the epicarp and the total content of vitamin C. In addition, negative correlations were found between hue and the carotenoid content of the pulp, and between hue and the antioxidant activity in the epicarp and pulp. Conclusion. The results suggest that a higher content of phenols, carotenoids, and vitamin C, together with a purple or red coloration of the epicarp, can all be associated with an increase in the antioxidant activities of the epicarp and pulp of the Mexican plum. Keywords: Mexico / Latin America / Mexican plum / Spondias purpurea / antioxidant activity / carotenoids / phenolics / vitamin C / nutritional value
    Full-text · Article · Sep 2015 · Fruits
    • "EWFs played a vital role in the diet of the people from prehistoric times. The use of EWFs has been significant for most human civilizations by making an important contribution to the health of local communities in many developing countries (Ali et al., 2008). Wild species Contents lists available at ScienceDirect journal homepage: "
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    ABSTRACT: This study documents the ethno-pharmacological importance of Edible Wild Fruits (EWFs) resource in the wild floral emporium of Swat, Khyber Pakhtunkhwa Northern Pakistan. This is imitated in the great diversity of plants used for medicinal purposes as well as in their wide range of therapeutic applications. Ethnomedicinal data was collected through semi-structured and open ended interviews, questionnaires, field surveys and local gatherings. Use value (UV), Relative importance (RI), Relative frequency of citation (RFC), Informant consensus factor (ICF) and Family importance value (FIV) was calculated to elaborate the EWFs, their families, disease treated and significant fruit species based on use reports by informants. A total of 47 species of EWFs belonging to 32 genera and 23 families were reported to be used in traditional medicines. Family Rosaceae dominated with 26% species followed by Moraceae (12%) and Rhamnaceae (10%), with mostly tree type of growth form (55%). The most consumed part of plants was fruit (72%) followed by leaves (21%). Decoction (26%) and unprocessed fruit (24%) were the major modes of crude drug preparation. The Informant consensus factor (ICF) of Joint/body aches was the highest followed by digestive disorders. Use value index of Vitis vinifera (3.8), being the highest, followed by Malus pumila (2) and Vitis parvifolia (2). The tradition of using EWFs in treating ailments is a common practice among the tribal communities, depending on the socio-economic conditions of the people. The multiple uses of these EWFs suggest further investigation regarding phytochemical analysis and pharmaceutical applications. Copyright © 2015. Published by Elsevier Ireland Ltd.
    No preview · Article · Jul 2015 · Journal of Ethnopharmacology
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    • "This plant is considered to be a remedy in tumors of rats (Bhandari, 1990; Ahmad & Basha, 2000). There are useful phyto-chemicals in it and thus help in easy urination, cures the asthma, as blood purifier and the aerial parts are of it are highly antioxidant in nature (Ali et al., 2008). The decoction of Parthenium hysterophorus is conventionally used in treatment of several diseases including dysentery, diarrhea, malaria and in urinary tract infections (Surib et al., 1996). "
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    ABSTRACT: Internal control genes are the constitutive genes which maintain the basic cellular functions and regularly express in both normal and stressed conditions in living organisms. They are used in normalization of gene expression studies in comparative analysis of target genes, as their expression remains comparatively unchanged in all varied conditions. Among internal control genes, actin is considered as a candidate gene for expression studies due to its vital role in shaping cytoskeleton and plant physiology. Unfortunately most of such knowledge is limited to only model plants or crops, not much is known about important medicinal plants. Therefore, we selected seven important medicinal wild plants for molecular identification of actin gene. We used gene specific primers designed from the conserved regions of several known orthologues or homologues of actin genes from other plants. The amplified products of ~370-380 bp were sequenced and submitted to GeneBank after their confirmation using different bioinformatics tools. All the novel partial sequences of putative actin genes were submitted to GeneBank [Parthenium hysterophorus (KJ774023), Fagonia indica (KJ774024), Rhazya stricta (KJ774025), Whithania coagulans (KJ774026), Capparis decidua (KJ774027), Verbena officinalis (KJ774028) and Aerva javanica (KJ774029)]. The comparisons of these partial sequences by Basic Local Alignment Search Tool (BLAST) and phylogenetic trees demonstrated high similarity with known actin genes of other plants. Our findings illustrated highly conserved nature of actin gene among these selected plants. These novel partial fragments of actin genes from these wild medicinal plants can be used as internal controls for future gene expression studies of these important plants after precise validations of their stable expression in such plants.
    Full-text · Article · Apr 2015 · Pakistan Journal of Botany
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