Cerebrospinal Fluid Enrichment Broth Cultures Rarely Contribute to the Diagnosis of Bacterial Meningitis

Division of Infectious Diseases and the Division of Hospital Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
The Pediatric Infectious Disease Journal (Impact Factor: 2.72). 03/2012; 31(3):318-20. DOI: 10.1097/INF.0b013e318243e502
Source: PubMed


This study included children undergoing lumbar puncture in the emergency department. Bacteria were isolated from 34 (1.7%) of 1898 cerebrospinal fluid (CSF) enrichment broth cultures; 30 were contaminants. The primary CSF Gram stain was negative in all specimens with a positive enrichment broth culture. Enrichment broth cultures rarely contributed to the diagnosis of bacterial meningitis, and positive CSF enrichment broth cultures contributed to diagnostic uncertainty.

17 Reads