Mycosporine and mycosporine-like amino acids: a paramount tool against ultra violet irradiation. Pharmacol Rev 5:138-146

ArticleinPharmacognosy Reviews 5(10):138-46 · July 2011with46 Reads
DOI: 10.4103/0973-7847.91107 · Source: PubMed


    Various facts demonstrated that UVB is harmful to organisms. Sunscreen compounds are usually used to prevent the excessive damage caused by UVB. However, certain photosynthetic organisms have evolved mechanisms to counteract the toxicity of ultraviolet radiation by synthesizing UV screening compounds such as mycosporine-like amino acids (MAAs). MAAs provide UV protection to primary and secondary consumers through food chain and to non-biological materials by photostabilizing action. Information related to the ecological consequence of MAAs and their spatial distribution from a wide range of organisms is accumulating. Hence, our studies seek a potent class of natural sun protective compounds to understand their relationship with environment and to develop a protocol for large-scale industrial production of these compounds so that they can find application as UV-protecting cosmetics.