Epithelial-myoepithelial parotid carcinoma after kidney transplantation

Department of Plastic, Aesthetic, Reconstructive, Maxilo-Facial Surgery, and Burn Unit, Hospital de São João, Porto, Portugal.
ecancermedicalscience (Impact Factor: 1.2). 08/2008; 2:92. DOI: 10.3332/ecancer.2008.92
Source: PubMed


The occurrence of a second malignant neoplasm (SMN) in patients who have been submitted to kidney transplantation is increasing and causes concern; parotid carcinoma is rarely reported after transplantation and may be related to long-term chemotherapy.
Salivary gland carcinomas displaying exclusively myoepithelial differentiation—myoepithelial carcinomas (EMC) are rare, being less than 1% of all salivary gland tumours. EMC arises most commonly in the parotid gland and usually occurs in women. Their histopathologic features, immunohistochemical profile and clinical behaviour remain controversial.