Magnetic resonance imaging appearance of scurvy with gelatinous bone marrow transformation

ArticleinSkeletal Radiology 41(3):357-60 · March 2012with32 Reads
Impact Factor: 1.51 · DOI: 10.1007/s00256-011-1350-9 · Source: PubMed


    Scurvy is a lethal but treatable disease that is rare in industrialized countries. Caused by vitamin C deficiency, it is most prevalent in persons of low socioeconomic status and smokers. Low levels of circulating vitamin C result in poor collagen fiber formation that, in turn, leads to demineralized bones, microfractures, and poor healing. Here we report a case of scurvy in a 5-year-old boy with normal radiographs in whom initial concern for leukemia based upon magnetic resonance imaging and clinical presentation led to a bone marrow biopsy revealing gelatinous transformation.