Subclinical depressive symptoms are common among older patients in primary care practices. This study examined the effects of a five-week Feldenkrais intervention on depressive symptoms (CES-D), perceived stress (PSS-10) and health-related quality of life (HRQoL) in independent living older adults. Participants (N=47) were randomly assigned to two groups: a Feldenkrais intervention (FG, n = 25) and a control group (waitlist) (CG, n = 22). HRQoL, CES-D and PSS-10 were assessed at baseline and after 5 weeks. Results of the mixed models indicated a significant Group X Time interaction for the CES-D (p=.009). No other significant Group X Time interactions were present. The effect size of the Feldenkrais intervention was .32, whereas the effect size for the control group was -.33 for symptoms of depression.