Translational Bioinformatics: Challenges and Opportunities for Case-Based Reasoning and Decision Support.

Conference Paper · January 2010with5 Reads
DOI: 10.1007/978-3-642-14274-1_1 · Source: DBLP
Conference: Case-Based Reasoning. Research and Development, 18th International Conference on Case-Based Reasoning, ICCBR 2010, Alessandria, Italy, July 19-22, 2010. Proceedings


    Translational bioinformatics is bioinformatics applied to human health. Although, up to now, its main focus has been to support
    molecular medicine research, translational bioinformatics has now the opportunity to design clinical decision support systems
    based on the combination of -omics data and internet-based knowledge resources. The paper describes the state-of-art of translational
    bioinformatics highlighting challenges and opportunities for decision support tools and case-based reasoning. It finally reports
    the design of a new system for supporting diagnosis in dilated cardiomyopathy. The system is able to combine text mining,
    literature search and case-based retrieval.