Efficient Information Processing in Retinal Neurons

Conference Paper · May 2009with11 Reads
DOI: 10.1109/VECIMS.2009.5068884 · Source: DBLP
Conference: IEEE International Conference on Virtual Environments, Human-Computer Interfaces and Measurement Systems, VECIMS 2009, Hong Kong, China, 11-13 May, 2009
Retina is the first stage for visual information processing in vertebrates. However, the retinal function is constrained by a number of factors such as the anatomic limitation, the metabolic limitation, and the noise in the neural circuitry. Our research is mainly focused to investigate the efficiency of information processing of the retinal neurons under such limitations and the related spatial and temporal patterns of the neural activities.
  • [Show abstract] [Hide abstract] ABSTRACT: Results from physiological, theoretical, and computational studies {suggest} that the visual cortex processes natural sensory information with a strategy of sparse coding. To investigate whether this is also the case for retinal ganglion cells (RGCs), neuronal activities were recorded from a group of chicken RGCs in response to natural, time-varying images (movies) using extracellular multi-electrode recording system. The response of single RGC in exposure to natural stimulation showed sparse activity, while the ensemble responses did not. Such result may suggest that at the RGC level, the single unit activity is kept at a low level in response to natural stimuli for energy-saving, but the neuronal population are often activated in a correlated manner to achieve efficient information transmission.
    Chapter · Jan 2008 · Brain Research
  • [Show abstract] [Hide abstract] ABSTRACT: In the present study, the spatiotemporal pattern of chicken retinal ganglion cells' firing activity in response to full-field white light stimulation was investigated. Cross-correlation analysis showed that ganglion cells of sustained subtype fired in precise synchrony with their adjacent neurons of the same subtype (delay lag within 2 ms, narrow correlation). On the other hand, the activities of neighboring ganglion cells of transient subtype were correlated with distributed time lags (10-30 ms, medium correlation). Pharmacological studies demonstrated that the intensity of the medium correlations could be strengthened when exogenous GABA was applied and attenuated when GABA receptors were blocked by picrotoxin. Meanwhile, the GABAergic modulation on the narrow correlations was not consistent. These results suggest that, in the chicken retina, GABAergic pathway(s) are likely involved in the formation of medium correlations between ganglion cells. Neurons might fire at a lower rate but with higher level of synchronization to improve the efficiency of information transmission, with the mechanism involving the GABAergic inhibitory input.
    Article · Nov 2007
  • [Show abstract] [Hide abstract] ABSTRACT: In the present study, the light responses of ganglion cells to chromatic stimulus were recorded from isolated retina of neonatal chick. It was found that for some non-color-opponent ganglion cells, the spatiotemporal patterns of the cells' light responses were related to the chromatic information that they received. When stimulus with some chromatic component was applied, some ganglion cells would generate distinguishable temporal patterns of light responses although these cells can be classified as non-color-opponent according to their light responses. The results suggest that in chick retina, the color information might be encoded not only by the color opponent ganglion cells, but also the spatiotemporal patterns of some ganglion cells that are traditionally classified as non-color-opponent subtype.
    Article · Nov 2005
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