This study explores whether organizations can employ job design strategies to relieve organizational stress for information technology IT professionals. The effect of flexible work schedule, employee support and training, and telecommuting as potential coping resources to relieve stress were studied. Perceived workload, role ambiguity, work facilitation, and decision latitude were drawn from previous studies as potential stressors of IT professionals. Perceived stress was measured by two commonly used measures: work exhaustion and depressed mood. The results suggest that removing role ambiguity and improving work-facilitation ease work-related stress. Allowing employees to have flexible work schedules was also found to ease their perceptions of workload. Employee support and training strategies were found to influence decision latitude and role ambiguity. Telecommuting did not have any effect on the stressors. Results also indicate that the association between work exhaustion and depressed mood was stronger for males than females.