ArticlePDF Available

Jasminum grandiflorum Linn (Chameli): Ethnobotany, Phytochemistry and Pharmacology – A review

  • January 2009
Authors:
Sandeep Sachan at Excellence Center of Pharmacy Lucknow
Sandeep Sachan
  • Excellence Center of Pharmacy Lucknow
Padmaa Paarakh at The Oxford Educational Institutions
Padmaa Paarakh
Download full-text PDFDownload full-text PDF
Read full-text
Download citation

Abstract

Summary Jasminum grandiflorum Linn (Chameli / Yasmin; Oleaceae) is native to Tropical and warm Temperate regions and cultivated in France, Italy, China, Japan, India, Morocco and Egypt. The plant is documented to possess beneficial effects as odontalgic, thermogenic, aphrodisiac, antiseptic, emollient, anthelmintic, deobstruant, suppurative, tonic, in fixing loose teeth, ulcerative stomatitis, leprosy, skin diseases, ottorrhoea, otalgia, wounds, corns and aromatherapy. Pharmacological activities of the plant reported so far are spasmolytic, antiinflammatory, anti-microbial, antioxidant, antiulcer, cytoprotective, chemoprotective, wound healing and anti-acne activity. The present review is an attempt to highlight the various ethnobotanical and traditional uses as well as phytochemical and pharmacological activities reported so far from J. grandiflorum.
Jasminum_grandiflorum_Linn_(Chameli)Ethnobotany_Phytochemistry_and_Pharmacology__A_revi
ew.pdf
Content uploaded by Sandeep Sachan
Author content
All content in this area was uploaded by Sandeep Sachan
Content may be subject to copyright.
Jasminum_grandiflorum_Linn_(Chameli)_Ethnobotany_Phytochemistry_and_Pharmacology__A_revi
ew.pdf
Content uploaded by Sandeep Sachan
Author content
All content in this area was uploaded by Sandeep Sachan
Content may be subject to copyright.
A preview of the PDF is not available
... Jasminum grandiflorum, commonly known as jasmine is a member of the Oleaceae family (Sadhu et al., 2007;Sandeep, 2009;Ferreres et al., 2014). Jasminum is a genus of shrubs and vines containingaround200 species found all over the world (Arun et al., 2016). ...
... Jasminum is a genus of shrubs and vines containingaround200 species found all over the world (Arun et al., 2016). J. grandiflorum is domestic to temperate and tropical areas including parts of Asia, Kashmir, Philippines, Myanmar and Sri Lanka (Sandeep, 2009;Arun et al., 2016). It is distributed across the west coast of India from south Canara to the low elevations of Kerala and is also cultivated in Italy, China, India, France, Egypt and Morocco (Somanadhan et al., 1998;Sandeep, 2009). ...
... J. grandiflorum is domestic to temperate and tropical areas including parts of Asia, Kashmir, Philippines, Myanmar and Sri Lanka (Sandeep, 2009;Arun et al., 2016). It is distributed across the west coast of India from south Canara to the low elevations of Kerala and is also cultivated in Italy, China, India, France, Egypt and Morocco (Somanadhan et al., 1998;Sandeep, 2009). The flower are harvested from July to November and from May to December in North and South India (Sandeep, 2009). ...
Potential angiotensin converting enzyme (ACE) inhibitors from Iranian traditional plants described by Avicenna's Canon of Medicine
Article
Full-text available
  • Jul 2019
Objective: Hypertension is an important cause of cardiovascular disorders. The angiotensin converting enzyme (ACE) plays an important role in hypertension; therefore, inhibition of ACE in treatment of chronically elevated blood pressure is an important therapeutic approach. In the current review, we have provided information from Persian Traditional Plants described by Avicenna in the Canon of Medicine and a number of more current scientific databases, with a focus on angiotensin converting enzyme inhibitory activity of the following six plants: Allium sativum, Cinnamomum zeylanicum, Jasminum grandiflorum, Tribulus terrestris, Vaccinium myrtillus and Vitis vinifera. Materials and methods: A literature search was conducted and information on different traditional plants used for hypertension was collected from the Canon of Medicine and several other databases including PubMed, Scopus, Google Scholar and Web of Science. Results: The present article highlights the antihypertensive potential of the above-noted six plants. Administered doses, manner of consumption, types of extracts, preparations and derivatives, personal habits, and other geographic and epidemiologic variables have an important role in the potential efficacy of these plants. Conclusion: Recent studies indicated a significant correlation between the traditional use of Persian plants to reduce blood pressure and angiotensin converting enzyme inhibitory activity.
View
... Many traditional herbal medicine researches recognized the beneficial effect of Jasmine Grandiflorum leaves on wound healing process [10]. Herbal treatment of aphthous ulcers by Jasmine Grandiflorum is also reported in traditional medicine [15]. ...
... In this research, all procedures abided by the ethical protocol in animal studies made by the committee of animal research and ethics (CARE) and American Psychological Association (APA) [15]. ...
Formulation of a Jasmine Grandiflorum containing mucoadhesive and evaluation of its healing effect on oral biopsy ulcers
Article
Full-text available
Objectives: The present research aimed to explore the effect of a mucoadhesive containing Jasminum grandiflorum leaves on the process of oral wound healing in animal samples. Materials and methods: The present double-blinded research was conducted on animals. To this aim, 28 rats were randomly selected and assigned to groups of control and experiment. The lesion was created by punch no. 3 in the midline of the mandibular labial mucosa of all mice. Each group received either a medicine or a placebo exclusively coded. The extent of contraction and wound healing was clinically assessed. To compare the two research groups, chi-squared test, repeated-measure ANOVA, and Mann-Whitney U test were run. SPSS software was used to do the statistical analyses. Results: Statistically significant differences were found between the percentage of wound contraction on the 3rd day (40.91% vs. 16.5%, p = 0.04) and the 7th day (92.9% vs. 69.2%, p = 0.05), wound recovery (57.1% vs. 21.4%, p = 0.05) and degree of inflammation on the 7th day (p = 0.00), type (p = 0.04) and thickness of epithelium (p = 0.00) and type of connective tissue (p = 0.00) on the 14th day. Conclusion: Investigations showed that the drug was more effective than the placebo in accelerating wound healing in clinical and histopathological terms. Clinical relevance: Accelerating wound healing in dental treatments and oral ulcers can also affect the quality of life of individuals.
View
... A review on the collection, techniques used for extraction of scent bearing molecules and their structures and a general review on the chemistry and legacy of methyl jasmonate and the synthetic hedione with parallel olfactory attributes 3 are available. The ethnobotany, phytochemistry and phytopharmacology of Jasminum grandiflorum has been reviewed briefly more recently 4,5 . ...
Jasminum grandiflorum review paper
Article
Full-text available
  • Jan 2020
Plants form the basis of human and animal life. Plants are better choice for medicinal applications when compared to synthetic chemicals and the nature has provided various types of medicinal plants. Jasminum grandiflorum Linn. (family Oleaceae) is a night bloomy flowering plant and is an important source of methyl jasmonates which find utility in plant defense, fruit ripening, plant growth senescence and other physical processes. The aroma plant Jasminum grandiflorum Linn. is native to tropical and warm temperate regions and the plant is observed to have favorable properties which can be used to treat numerous ailments. The leaves of the plant find clinical use in Ayurveda for wound management. The flowers of the plant are used to adorn the women coiffure. In this article, an attempt has been made to provide an updated review on this plant with focus on the isolation and quantification of chemical constituents, medicinal potential and patents on the medicinal and cosmetic formulations comprising Jasminum grandiflorum Linn.
View
... A review on the collection, techniques used for extraction of scent bearing molecules and their structures and a general review on the chemistry and legacy of methyl jasmonate and the synthetic hedione with parallel olfactory attributes 3 are available. The ethnobotany, phytochemistry and phytopharmacology of Jasminum grandiflorum has been reviewed briefly more recently 4,5 . ...
JASMINUM GRANDIFLORUM LINN. – AN UPDATE REVIEW
Article
Full-text available
  • May 2020
JASMINUM GRANDIFLORUM LINN. – AN UPDATE REVIEW
View
... ("Spanish jasmine" or "Royal jasmine") is a plant of Oleaceae family. Its classical names are Jati, Malti or Rajputrika (Paarakh and Paarakh, 2009) and its flowers and leaves are widely used in folk medicine to prevent and treat breast cancers. Flowers are also useful in uterine bleeding when brewed as tonic (Mishra et al., 2010). ...
Effects of ethanolic extract of Jasminum grandiflorum Linn. flowers on wound healing in diabetic Wistar albino rats
Article
Full-text available
  • Sep 2017
Objective To evaluate wound healing activity of ethanolic extract of Jasminum grandiflorum Linn. (J. grandiflorum) flowers in diabetic rats. Materials and Methods Streptozotocin-induced diabetic Wistar albino rats were divided into six groups (n=6).Three groups – diabetic control, positive control (that received Glibenclamide) and treatment (that received J. grandiflorum Linn. Flower extract) were operated for excision wounds (EW). These groups were evaluated for wound contraction and re-epithelization. The other three groups were operated for incision wounds (IW) and dead space wounds (DW). Incision and dead space wounds were produced in the same rats. IWs were analyzed for wound breaking strength and the granulation tissues from DWs were analyzed for dry weight, hydroxyproline content, and histology. Results IWs and DWs showed significant improvement in wound breaking strength (265.8±10.4 vs 332.5±8.2; p<0.05), granulation tissue dry weight (26.1±0.6vs 40.4±0.3; p<0.01) and hydroxyproline content (19.3±0.5 vs 32.6±0.8; p<0.01) in treatment group as compared to control group. Neo-angiogenesis was also high in treatment group. Wound contraction was earlier (day 14) in treatment group compared to diabetic control (day 20). No significant improvement was seen in re-epithelization in treatment group. Conclusion Ethanolic extract of J. grandiflorum Linn. flowers increases granulation tissue formation as well as neo-angiogenesis. It also enhances wound contraction; however, re-epithelization was not significantly affected. J. grandiflorum Linn. flowers could be potentially effective in promotion of diabetic wounds healing by increasing granulation tissue formation and enhancing wound contraction; however, further studies are required for its clinical application.
View
Specific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata
Article
Full-text available
The native diploid tobacco Nicotiana attenuata produces abundant, potent anti-herbivore defense metabolites known as 17-hydroxygeranyllinalool diterpene glycosides (HGL-DTGs) whose glycosylation and malonylation biosynthetic steps are regulated by jasmonate signaling. To characterize the biosynthetic pathway of HGL-DTGs, we conducted a genome-wide analysis of uridine diphosphate glycosyltransferases (UGTs) and identified 107 family-1 UGT members. The transcript levels of three UGTs were highly correlated with the transcript levels two key HGL-DTG biosynthetic genes: geranylgeranyl diphosphate synthase (NaGGPPS) and geranyllinalool synthase (NaGLS). NaGLS's role in HGL-DTG biosynthesis was confirmed by virus-induced gene silencing. Silencing the UDP-rhamnosyltransferase gene UGT91T1 demonstrated its role in the rhamnosylation of HGL-DTGs. In vitro enzyme assays revealed that UGT74P3 and UGT74P4 use UDP-glucose for the glucosylation of 17-hydroxygeranyllinalool (17-HGL) to lyciumoside I. Plants with stable silencing of UGT74P3 and UGT74P5 were severely developmentally deformed, pointing to a phytotoxic effect of the aglycone. The application of synthetic 17-HGL and silencing of the UGTs in HGL-DTG-free plants confirmed this phytotoxic effect. Feeding assays with tobacco hornworm (Manduca sexta) larvae revealed the defensive functions of the glucosylation and rhamnosylation steps in HGL-DTG biosynthesis. Glucosylation of 17-HGL is therefore a critical step that contributes to the resulting metabolites' defensive function and solves the autotoxicity problem of this potent chemical defense.
View
Jasmine ( Jasminum grandiflorum ) Flower Extracts Ameliorate Tetradecanoylphorbol Acetate Induced Ear Edema in Mice
Article
Full-text available
  • Apr 2020
Published data from in vitro assays support the anti-inflammatory effects of jasmine ( Jasminum grandiflorum Linn.) but limited studies are reported in animal models. Herein, the anti-inflammatory effects of jasmine flower extracts (JFEs) including ethanol extract (JF-EE), petroleum ether extract (JF-PEE), ethyl acetate extract (JF-EAE), and n-butanol extract (JF-BE) were evaluated in a mouse ear edema model. Acute mouse ear skin inflammation was induced by tetradecanoylphorbol acetate (TPA; 125 µg/mL) and then treated with JFEs (100 mg/mL) or dexamethasone (DEX; 6.25 mg/mL; as a positive control). Jasmine flower extracts alleviated ear edema by reducing TPA-increased ear thickness and ear weight by 30.8% to 64.1% and 24.0% to 47.1%, respectively, whereas DEX showed comparable activity (by 71.8% and 49.1%, respectively). Their anti-inflammatory effects were supported by data from the immunohistochemical assays. Jasmine flower extracts reduced the inflammatory cells (from 5.5- to 9.5-fold) and the expressions of inflammation related enzymes including cyclooxygenase-2 and inhibitor of kappa-B kinase (from 1.9- to 2.8-fold and from 7.1- to 11.0-fold, respectively). Findings from this study showed that JFEs were able to ameliorate TPA-induced mouse skin inflammation. However, future studies on the underlying mechanisms of jasmine flower’s anti-inflammatory effects are warranted.
View
View
Exploratory Studies on the in Vitro Anti-inflammatory Potential of Two Herbal Teas ( Annona muricata L. and Jasminum grandiflorum L.), and Relation with Their Phenolic Composition
Article
  • Feb 2017
The need of new anti-inflammatory drugs has led to the search for safer and more potent molecules in distinct sources, such as natural products. This work aimed to explore the anti-inflammatory potential of aqueous extracts from two herbal teas (Annona muricata L. and Jasminum grandiflorum L.) in RAW 264.7 macrophages cells and in cell-free assays. Furthermore, the phenolic composition of both extracts and of their hydrolysates was characterized by HPLC-DAD, in order to establish possible relationships with the biological activity. In a general way, A. muricata displayed a stronger capacity to inhibit nitric oxide (NO) production and the activity of phospholipase A2 (PLA2 ), displaying an IC50 of 142 μg/mL against this enzyme. A deeper look at phenolic compounds revealed that aglycones had more capacity to inhibit NO and PLA2 than their corresponding glycosides, quercetin being clearly the most potent one (IC50 = 7.47 and 1.36 μM, respectively). In addition, 5-O-caffeoylquinic acid, at 1.56 μM, could also inhibit PLA2 (ca. 35%). Our findings suggest that the consumption of both herbal teas may be a preventive approach to inflammatory disorders. This article is protected by copyright. All rights reserved.
View
A review on anti-acne potential of medicinal plant extracts against propionibacterium acnes
Article
Acne vulgaris (Acne) is the most common skin disorder characterized by noninflammatory comedones or inflammatory papules, pustules and nodules. Although acne does not pose serious threat to general health, it is one of the most socially distressing conditions especially for adolescents. The acne inflammation is triggered by pus forming bacteria recognized as Propionibacterium acnes and Staphylococcus epidermidis. Acne therapy includes prolonged use of comedolytic agents, antibiotics and anti-inflammatory agents that are known to cause many side effects. Moreover, the widespread and long-term use of antibiotics over the years has unfortunately led to emergence of resistant strains. To avoid side effects, traditional or herbal formulations are preferred. Herbs are safe, efficacious and multifunctional. Medicinal plant extracts are known to have enormous therapeutic potential. Plant-based preparations with little or no side effects are cyclically returning to complement dermatological therapy. They serve as safer choice or in some cases is the only effective treatment.
View
View
View
View
View
View
View
View
View
Pharmacognostical studies on the leaves of Jasminum grandiflorum Linn.
Article
  • Jan 1995
Pharmacognostical studies carried out on the leaves of Jasminum grandiflorum Linn. commonly used as crude drug by the name 'Chameli' have been described and discussed. The macro and microscopic characters of the leaf, fluorescence characteristics under UV light and other features of powdered drug, qualitative estimation of organic and inorganic chemical constituents, some other physico-chemical constants and results of thin layer chromatography have been described in detail.
View
Indole oxygenase from the leaves of Jasminum grandiflorum
Article
An indole oxygenase from the leaves of Jasminum grandiflorum was isolated and purified to near homogeneity. The purified enzyme system catalyses the conversion of indole to anthranilic acid. It is optimally active at pH 4.8 and at 30°C. Apart from indole, the oxygenase also attacks 5-hydroxy indole and 5-bromoindole. Both sulfhydryl reagents and sulfhydryl compounds inhibited the enzyme activity. Copper specific metal chelators such as salicylaldoxime, diethyl dithiocarbamate and neocuproine, inhibited the enzyme activity drastically. Inhibition caused by atebrine, could be reversed by FAD. Dialysis resulted in complete loss of enzyme activity. Inactive enzyme could be reactivated only by the addition of both FAD and Cu2+, suggesting that indole oxygenase is a cuproflavoprotein.
View