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Antioxidant activity of the medicinal plant Coleus forskohlii Briq

Authors:
  • Government General Degree College, Singur, West Bengal, India
  • Munzur University- Tunceli Turkey

Abstract

Antioxidant status of different parts of Coleus forskohlii including roots, stem, leaves and tubers was analyzed. For the enzymatic antioxidant properties, the activities of superoxide dismutase, peroxidase, polyphenol oxidase and catalase were significantly higher (P < 0.05) in tubers than in the leaves, roots and stem. Among the non-enzymatic antioxidants, except for the chlorophyll and lycopene content, the reducing power and chelating abilities on Fe2+, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity, total phenol, flavonoids and �-carotene were significantly higher (P < 0.05) in tubers than in the leaves, roots and stem, respectively. The tubers possessed significantly rich sources of both enzymatic and non-enzymatic antioxidants besides their medicinal properties.
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... mg GAE/gm). Studies showed that many flavonoids and related polyphenols contribute significantly to the total antioxidant activity of many plants [22]. Phenols contain good antioxidant, antimutagenic and anticancer properties, therefore, the highest content of total phenol in tubers is held responsible for better antioxidant characteristics [22]. ...
... Studies showed that many flavonoids and related polyphenols contribute significantly to the total antioxidant activity of many plants [22]. Phenols contain good antioxidant, antimutagenic and anticancer properties, therefore, the highest content of total phenol in tubers is held responsible for better antioxidant characteristics [22]. Flavonoids are considered the major group of phenolic compounds for their antiviral, antimicrobial, and spasmolytic properties, while alkaloids are commonly found to have antimicrobial properties [23]. ...
... Various plants have already been proved to have high antioxidant activity with high amounts of phenolics and flavonoids [21]. The total phenol content was significantly higher (P<0.05) in the tubers (27.05 μg catechol equivalents/gm dry tissue) compared to roots (24.22 μg catechol equivalents/gm dry tissue) and stem (21.26 μg catechol equivalents/gm dry tissue) [22]. The stems of C. aromaticus showed higher content of total polyphenols (62.12 mg/gm fw) compared with C. forskholii (31.32 mg/gm fw) and C. zeylanicus (48.5 mg/gm fw) [24]. ...
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... Plants' impacts on the human body are related to their chemical components. Herbal medicines are thought to be highly safe and have a substantial effect on the treatment of various illnesses [197]. Traditional medicine is still extensively practiced today, and plants are still regarded as a key source of natural antioxidants that may serve as a guide for creating new medicines [198]. ...
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... Plants and plants derived products are used by men for their basic requirements. The use of traditional medicine is wide spread and plants are still a large source of natural antioxidants that might serve as leads for the development of novel drugs [1]. In fact, medicinal plants are considered to be the main sources of several phytochemical compounds like alkaloids, tannins, phenols, saponin, coumarins, steroids and flavonoids curing diversified chronic diseases [2]. ...
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... Most of these metabolites contain phenolic rings and are natural antioxidants. There is need to isolate them in pure state which would leads to the development of novel drugs [29]. Natural antioxidants are potentially safe as they have limited side effects, efficient in term of their efficacies and inexpensive as they are obtained from renewable sources. ...
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