Submandibular swelling and its differential diagnosis


The lump in the submandibular area is not too unusual. Nonmalignant swelling may be caused by mumps, sialadenitis, Sjögren syndrome, cysts and infections. Submandibular lymphadenopathy may also result from infections of teeth, upper respiratory track, sinuses and tonsils or infections mononucleosis and cut scratch disease. The neoplastic growths in the submandibular area may include in most of the case tumors of the submandibular gland, the tail of the parotid gland, the Hodgkin's disease and non-Hodgkin's lymphomas. However, since the greatest cause of asymmetric submandibular enlargement, especially in people elder than 40 years old is the metastatic disease, the physician should always first seek to eliminate a primary site in the head, face and mouth area. Possible origin from other parts of the body should also be ruled out. In this article we are presenting representative cases of submandibular swelling.

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    • "Nonmalignant swelling may occur as sialadenitis, Sjögren syndrome, cysts, infections, and lymphadenopathy. Neoplastic growths such as the SMG, the tail parotid gland, the Hodgkin's disease, non-Hodgkin's lymphomas, and metastatic disease may be seen [7]. Some rare cases of submandibular swelling have been seen as submandibular localizations of thyroid lesions [8]. "
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    ABSTRACT: Background. Congenital absence of the submandibular gland (SMG) is a rare condition. Although complaints such as dry mouth, dental problems, or difficulty in swallowing may be seen, the subjects may also be asymptomatic. The absence of the SMG may be associated with hypertrophy of the contralateral SMG. Case Report. We report the case of a 44-year-old woman with incidentally detected left SMG aplasia, with contralateral SMG hypertrophy mimicking a mass, and the case of a 46-year-old woman with incidentally detected bilateral SMG aplasia, demonstrated by computerized tomography (CT) and magnetic resonance imaging (MRI). Conclusion. It is important for the clinician to know that this very rare abnormality may exist. When such a case is encountered, symptoms and findings should be reevaluated and, if necessary, conservative therapy should be initiated. The possibility of observing additional deformities should be kept in mind and an evaluation should be done for other cases in the family.
    Full-text · Article · Sep 2014