HLA typing in Actinic Prurigo

ArticleinJournal of the American Academy of Dermatology 22(6 Pt 1):1019-23 · July 1990with5 Reads
Impact Factor: 4.45 · DOI: 10.1016/0190-9622(90)70144-7 · Source: PubMed


    Thirty-two actinic prurigo patients of Cree ancestry underwent human lymphocyte antigen (HLA) typing and were compared with 32 control subjects of Cree ancestry. We found a significantly increased frequency of HLA-A24 and Cw4 antigens and a significant decrease in the frequency of the A3 antigen in actinic prurigo patients. These HLA associations may be helpful in determining whether actinic prurigo is a distinct disease or a variant of polymorphous light eruption.