Benign adrenal lesions mimicking malignancy on MR imaging: Report of two cases
Radiology (Impact Factor: 6.87). 07/1987; 163(3):669-71. DOI: 10.1148/radiology.163.3.3575711
Two cases of nonmalignant adrenal masses with prolonged T2 relaxation time and increased adrenal/liver signal ratios are reported. These two cases, one a functioning adenoma with small areas of hemorrhage and the other tuberculosis, emphasize that increased signal intensity in an adrenal mass on T2-weighted images is not always due to malignancy or a pheochromocytoma. While the signal characteristics of an adrenal mass are useful in distinguishing malignancy or pheochromocytoma from benign adenomas, other studies (such as computed tomography for the detection of hemorrhage), clinical evaluation, and percutaneous biopsy remain useful in the investigation of an adrenal mass.
Article: CT and MRI of adrenal lesions[Show abstract] [Hide abstract]
ABSTRACT: Adrenal lesions can be divided into those that result in clinical syndromes due to excess hormone elaboration and those that are nonhyperfunctioning. Computed tomography (CT) is usually adequate to assess the adrenal glands in patients with hyperfunctional disease. Occasionally supplementation with radionuclide studies, magnetic resonance (MR) or venous sampling, is required. Lesions which are not hyperfunctioning are often detected as an incidental mass. The CT and MR characteristics often allow a confident diagnosis based on their imaging characteristics. The adrenal glands are a common site of metastatic disease which can be detected by CT and further characterized by MR or biopsy if the stage of disease is uncertain.
Article: MRI of the adrenal glands
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ABSTRACT: The adrenal gland consists of cortical and medullary components, both of which may be functionally imaged using radiopharmaceuticals designed to take advantage of the specialized physiology of each tissue. Radiolabeled cholesterol derivatives are taken up by normal and abnormal adrenal cortex and provide an in vitro map of adrenocortical function in Cushing's Syndrome, hyperaldosteronism, and hyperadrenogenism. Quantification of uptake shows strong correlation with biochemical parameters of adrenocortical hyperfunction. In the case of incidentally discovered euadrenal masses scintigraphy may help to distinguish between benign, nonfunctional cortical adenomas, and destructive, potentially malignant lesions. Radiolabeled metaiodobenzylguanidine (MIBG) is a tracer of type I uptake and intracellular storage capacity for catecholamines in sympathomedullary tissues and tumors derived from this system. This permits the location of pheochromocytomas of all types (benign and malignant, intra- and extra-adrenal, sporadic and familial) as well as neuroblastomas in all stages. Other neuroendocrine tumors with type I uptake capacity may also be imaged. In suitable cases preliminary data suggests the administration of large doses of MIBG may permit internal radiotherapy of otherwise untreatable neuroendocrine tumors.
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