The study of the phonoprosodic structure of spontaneous speech of infants wearing cochlear implants comprises a fresh attempt to record and analyze premature speech for diagnostic and interventional purposes. This study of prelinguistic speech for typically developing infants and those with cochlear implants is not easy since the traditional linguistic tools of analysis based on adult language cannot be used readily for the accurate description of adult speech. Therefore, the present Thesis proceeds to the analysis of infant speech through acoustical and auditory analysis based on the principles of the infraphonological model of Oller (2000). The innovation of the Thesis lies in the analysis of infant speech of protophones of typically developing infants wearing cochlear implants, contributing both to international and to the substantially lacking Greek bibliography.It is acknowledged nowadays that prosodic fluctuations consist of the basic communication characteristic of the infant, either during perception or production of speech. Consequently, for the present Thesis, it was necessary to analyze the prosodic features of protophones, which dominate during infantile speech. This analysis was performed through the protophone prosodic characteristics of duration and pitch. More specifically, the particular objectives of the Thesis were a) to record the structures of canonical babbling in infants and children of very young age with cochlear implants concerning the syllabic sequence of consonants and vowels, b) to analyze the range of prosodic fluctuations of protophones mainly of canonical babbling, c) to analyze their duration, d) to compare all the above features with a control group of typically developing infants to determine whether the trajectory of the protophone development in children with cochlear implants follows a normal or deviant, peculiar course and finally, e) to present a comparison between infants implanted before or after the 24 months of chronological age since older researches indicated that more benefits emerged from cochlear implantation to the first group rather than the second one.Overall, three typically developing infants (TD) participated, aged 0:8-1:1 and seven infants wearing cochlear implants, with chronological age at the beginning of recordings 1:10-4:0 years and post-implantation age from the beginning until the completion of the study 0:0-1:3 years. The children were selected as candidates to receive a cochlear implant under the criteria of the ENT clinic protocol of the AHEPA University Hospital in Thessaloniki. They were not diagnosed with any other developmental disorder apart from deafness; pre-operatively, the children had PTA 95-110 dB ΗL and did not benefit from using simple acoustic devices. The recordings of spontaneous productions were performed through appropriate equipment in a familiar environment (home), at frequent periods, and through interaction with caregivers. The post-implantation age of infants with cochlear implants was matched with the hearing age of typically developing infants, covering the first year eventually. After data collection, acoustical analysis was performed using appropriate speech analysis software (Praat). Thus, both the duration and pitch differences of protophones were measured. Furthermore, the number of protophones was classified based on the number of syllables of each protophone type via wide-band spectrography aiming to identify the most frequent use of protophone syllabic structure in the Greek language. For the completion and diffusion of the research results, all the rules of anonymity and consent forms of the participants were followed and gathered.Concerning the results, very satisfactory agreement rates among the raters were initially noted. The findings of the present Thesis indicated a) a tendency of infants with cochlear implants to produce isolated vowels of longer duration compared to typically developing peers. This fact was regarded as a weakness for infants with implants since shorter duration comprises a sample of greater maturity of the speaker. In addition, b) the disyllable structure CVCV was found to be the most frequent protophone type of speech over the first year post-operatively, whether the infants received the implant before or after 24 months of chronological age. However, this conclusion aligns with the outcomes for the Greek language through typical development. Also, c) the appearance of the monosyllable structure of CV recorded since the beginning of the first stages of prelinguistic speech in children with cochlear implants. d) There was no significant statistical difference between the mean pitch difference of typically developing infants and the CI1 infants (a group with earlier implantation). This assumption suggests that when cochlear implantation is performed in children younger than two years old, it may be compared with the performance of children with normal hearing. The respective mean pitch difference of the CI2 group was also not significantly different from that of typically developing infants. This result suggests that these infants are destined to adopt linguistic behaviours based on the characteristics of the dominant language. At the same time, maturity-related factors should be considered (chronological age at the beginning of recordings 2:1-4:0 years).In contrast to previous studies based on typical development, which argued for only one syllable type at each stage of prelinguistic speech, the present Thesis e) recorded the simultaneous co-existence of multi-syllable types of protophones. This finding relates to the second half of the first year of development of typically developing infants and to the first post-operative year of infants with CIs.Quantitative classification of protophones with the parallel evaluation of their suprasegmental features through acoustic and auditory analyses provides a new reliable perspective for comparing populations with similar hearing experiences. These comparisons of high diagnostic value can equip us with new linguistic information about disordered speech. In their turn, this information can positively contribute to the formation and design of new evaluation and intervention techniques useful to speech pathology (which have not been developed yet for the Greek language) and audiology.